{{Rsnum
|rsid=17810546
|Chromosome=3
|position=159947262
|Orientation=plus
|GMAF=0.05096
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene=IL12A-AS1
|Gene_s=IL12A-AS1
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 81.5 | 16.9 | 1.5
| HCB | 100.0 | 0.0 | 0.0
| JPT | 100.0 | 0.0 | 0.0
| YRI | 100.0 | 0.0 | 0.0
| ASW | 0.0 | 0.0 | 0.0
| CHB | 100.0 | 0.0 | 0.0
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 0.0 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}{{GWAS Summary
|SNP=rs17810546
|PubMedID=18311140
|Condition=Celiac disease
|Gene=IL12A, SCHIP1
|Risk Allele=G
|pValue=1.00E-009
|OR=1.35
|95CI=1.23-1.49
|OA=1
}}

{{omim
|desc=CELIAC DISEASE, SUSCEPTIBILITY TO, 10; CELIAC10
|id=612008
|rsnum=17810546
}}

{{PharmGKB
|RSID=rs17810546
|Name_s=
|Gene_s=-
|Feature=
|Evidence=PubMed ID:18311140; Web Resource:http://www.genome.gov/gwastudies/
|Annotation=GWAS Results: Newly identified genetic risk variants for celiac disease related to the immune response (Initial Sample Size: 767 cases, 1,422 controls; Replication Sample Size: 1,643 cases, 3,406 controls; Risk Allele: rs17810546-G).
|Drugs=
|Drug Classes=
|Diseases=Celiac Disease
|Curation Level=Non-Curated
|PharmGKB Accession ID=PA162356755
}}

{{PMID Auto GWAS
|PMID=20190752
|Trait=Celiac disease
|Title=Multiple common variants for celiac disease influencing immune gene expression
|RiskAllele=G
|Pval=4E-28
|OR=1.36
|ORtxt=[1.29-1.44]
|OA=1
}}

{{omim
|id=212750
|rsnum=17810546
}}

{{PMID Auto
|PMID=22087237
|Title=Improving the estimation of celiac disease sibling risk by non-HLA genes
|OA=1
}}

{{PMID Auto
|PMID=18713140
|Title=Translational mini-review series on the immunogenetics of gut disease: immunogenetics of coeliac disease.
|OA=1
}}

{{PMID Auto
|PMID=18853133
|Title=Gene variants influencing measures of inflammation or predisposing to autoimmune and inflammatory diseases are not associated with the risk of type 2 diabetes.
|OA=1
}}

{{PMID Auto
|PMID=19073967
|Title=Shared and distinct genetic variants in type 1 diabetes and celiac disease.
|OA=1
}}

{{PMID Auto
|PMID=19458352
|Title=Primary biliary cirrhosis associated with HLA, IL12A, and IL12RB2 variants.
|OA=1
}}

{{PMID Auto
|PMID=19468064
|Title=Parasites represent a major selective force for interleukin genes and shape the genetic predisposition to autoimmune conditions.
|OA=1
}}

{{PMID Auto
|PMID=20647273
|Title=Investigation of type 1 diabetes and coeliac disease susceptibility loci for association with juvenile idiopathic arthritis.
|OA=1
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs17810546
|overall_frequency_n=3
|overall_frequency_d=128
|overall_frequency=0.0234375
|n_genomes=4
|n_genomes_annotated=0
|n_haplomes=4
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|in_pharmgkb=Y
|autoscore=2
|webscore=N
|n_web_uneval=10
}}

{{PMID Auto GWAS
  |PMID=23291587
  |Trait=Behcet's disease
  |Title=Genome-wide association analysis identifies new susceptibility loci for Behçet's disease and epistasis between HLA-B*51 and ERAP1.
  |RiskAllele=A
  |Pval=6E-7
  |OR=1.55
  |ORtxt=[1.30-1.85]
  |OA=1
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}