{{Rsnum
|rsid=179008
|Gene=TLR7
|Chromosome=X
|position=12885540
|Orientation=plus
|ReferenceAllele=A
|MissenseAllele=T
|GMAF=0.1518
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;T)
|geno3=(T;T)
|Gene_s=TLR7
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;T)
| geno3=(T;T)
| CEU | 72.3 | 21.5 | 6.2
| HCB | 100.0 | 0.0 | 0.0
| JPT | 100.0 | 0.0 | 0.0
| YRI | 76.2 | 9.5 | 14.3
| ASW | 0.0 | 0.0 | 0.0
| CHB | 100.0 | 0.0 | 0.0
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 0.0 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}
{{PMID Auto
|PMID=19473567
|Title=Investigation of TLR5 and TLR7 as candidate genes for susceptibility to systemic lupus erythematosus
}}

{{PMID Auto
|PMID=20595247
|Title=Polymorphisms of innate pattern recognition receptors, response to interferon-beta and development of neutralizing antibodies in multiple sclerosis patients
}}
{{PMID Auto
|PMID=20872712
|Title=Toll-like receptor 7 rs179008/Gln11Leu gene variants in chronic hepatitis C virus infection
}}

{{PMID Auto
|PMID=18385087
|Title=Toll-like receptor polymorphisms and age-related macular degeneration.
}}

{{PMID Auto
|PMID=18682521
|Title=Association analysis identifies TLR7 and TLR8 as novel risk genes in asthma and related disorders.
}}

{{PMID Auto
|PMID=19505919
|Title=Toll-like receptor signaling pathway variants and prostate cancer mortality.
|OA=1
}}

{{PMID Auto
|PMID=21872627
|Title=Association of polymorphisms in TLR genes and in genes of the Toll-like receptor signaling pathway with cancer risk.
}}

{{PMID Auto
|PMID=22065095
|Title=TLR7/8/9 polymorphisms and their associations in systemic lupus erythematosus patients from southern Brazil.
}}

{{GET Evidence
|gene=TLR7
|aa_change=Gln11Leu
|aa_change_short=Q11L
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs179008
|overall_frequency_n=1584
|overall_frequency_d=8761
|overall_frequency=0.180801
|n_genomes=11
|n_genomes_annotated=0
|n_haplomes=15
|n_articles=0
|n_articles_annotated=0
|pph2_score=0.002
|nblosum100=5
|autoscore=0
|webscore=N
}}

{{PMID Auto
|PMID=24071890
|Title=﻿TLR7 Gln11Leu single nucleotide polymorphism in patients with sarcoidosis
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | HumanOmni1Quad}}