{{Rsnum
|rsid=1799899
|Gene=TF
|Chromosome=3
|position=133756968
|Orientation=plus
|ReferenceAllele=G
|MissenseAllele=A
|GMAF=0.03581
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=TF
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 0.9 | 6.2 | 92.9
| HCB | 0.0 | 0.0 | 100.0
| JPT | 0.0 | 0.0 | 100.0
| YRI | 0.0 | 0.0 | 100.0
| ASW | 0.0 | 1.8 | 98.2
| CHB | 0.0 | 0.0 | 100.0
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 10.9 | 89.1
| LWK | 0.0 | 0.9 | 99.1
| MEX | 0.0 | 5.3 | 94.7
| MKK | 0.0 | 3.2 | 96.8
| TSI | 1.0 | 15.7 | 83.3
| HapMapRevision=28
}}{{omim
|desc=IRON DEFICIENCY ANEMIA, SUSCEPTIBILITY TO
|id=190000
|rsnum=1799899
|variant=0008
}}

The A allele of [[rs1799899]], also known as the human transferrin G277S mutation, is associated with iron deficiency anemia {{PMID|11703331}}, lower total iron binding capacity (TIBC), and anemia in menstruating white women.

{{PMID Auto GWAS
|PMID=21665994
|Trait=None
|Title=Genome-wide association study identifies two loci strongly affecting transferrin glycosylation.
|RiskAllele=A
|Pval=1E-9
|OR=0.4020
|ORtxt=[0.27-0.53] unit decrease
|OA=1
}}

{{ClinVar
|rsid=1799899
|Reversed=0
|FwdREF=G
|FwdALT=A
|REF=G
|ALT=A
|RSPOS=133475812
|CHROM=3
|GMAF=0.0357
|dbSNPBuildID=89
|SSR=0
|SAO=1
|VP=0x050368000000150517130100
|GENEINFO=TF:7018
|GENE_NAME=TF
|GENE_ID=7018
|WGT=0
|VC=SNV
|CLNALLE=1
|CLNHGVS=NC_000003.11:g.133475812G>A
|CLNORIGIN=1
|Tags=PM;PMC;S3D;SLO;VLD;G5;HD;GNO;KGPhase1;KGPROD;OTHERKG;PH3;LSD;MTP;OM
|CAF=0.9642; 0.03581
|CLNACC=RCV000013457.1
|CLNDBN=Reclassified - variant of unknown significance
|CLNSRC=OMIM Allelic Variant
|CLNSRCID=190000.0008
|COMMON=1
|Disease=Reclassified - variant of unknown significance
}}

{{PMID Auto
|PMID=17601350
|Title=A genetic association analysis of cognitive ability and cognitive ageing using 325 markers for 109 genes associated with oxidative stress or cognition.
|OA=1
}}

{{GET Evidence
|gene=TF
|aa_change=Gly277Ser
|aa_change_short=G277S
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs1799899
|overall_frequency_n=363
|overall_frequency_d=10758
|overall_frequency=0.0337423
|n_genomes=2
|n_genomes_annotated=0
|n_haplomes=2
|n_articles=0
|n_articles_annotated=0
|in_omim=Y
|pph2_score=0.999
|nblosum100=2
|autoscore=4
|webscore=N
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}