{{Rsnum
|rsid=1799913
|Gene=TPH1
|Chromosome=11
|position=18025708
|Orientation=minus
|GMAF=0.3581
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|Summary=heroin addiction in hispanics
|geno1=(A;A)
|geno2=(A;C)
|geno3=(C;C)
|Gene_s=TPH1
}}commonly referred to as A779C

Only for Hispanics, individuals who have a genoset composed of [[rs1799913]](C;C) and [[rs7963720]](T;T) are reported to be at 14x higher risk for developing heroin [[addiction]] (CI:0.83-244.63, p=0.012).{{PMID|18181017}}

Again, only for Hispanics, individuals having a genoset composed of [[rs1799913]](C;C) and [[rs4290270]](T;T) are reported to be at 9x higher risk for developing heroin addiction (CI:0.5-153, p=0.063).{{PMID|18181017}}
{{ neighbor
| rsid = 1800532
| distance = 561
}}

{{omim
|desc=MAJOR DEPRESSIVE DISORDER; MDD
|id=608516
|rsnum=1799913
}}

{{omim
|desc=TRYPTOPHAN HYDROXYLASE 1; TPH1
|id=191060
|rsnum=1799913
}}

{{PMID|17521439|OA=1
}} Association between 5-HT2A, TPH1 and GNB3 genotypes and response to typical neuroleptics: a serotonergic approach.

{{PMID|20580984}} Tryptophan hydroxylase gene 1 (TPH1) variants associated with cerebrospinal fluid 5-hydroxyindole acetic acid and homovanillic acid concentrations in healthy volunteers.

{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | HumanOmni1Quad}}