{{Rsnum
|rsid=1799941
|Gene=SHBG
|Chromosome=17
|position=7630105
|Orientation=plus
|GMAF=0.124
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=SHBG
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 5.3 | 34.5 | 60.2
| HCB | 0.0 | 1.5 | 98.5
| JPT | 0.0 | 0.0 | 0.0
| YRI | 0.0 | 5.4 | 94.6
| ASW | 1.8 | 8.8 | 89.5
| CHB | 0.0 | 1.5 | 98.5
| CHD | 0.0 | 0.0 | 0.0
| GIH | 3.0 | 20.8 | 76.2
| LWK | 0.0 | 4.5 | 95.5
| MEX | 0.0 | 26.3 | 73.7
| MKK | 0.6 | 14.1 | 85.3
| TSI | 6.9 | 43.1 | 50.0
| HapMapRevision=28
}}{{PMID Auto
|PMID=19574343
|Title=Quantitative trait loci predicting circulating sex steroid hormones in men from the NCI-Breast and Prostate Cancer Cohort Consortium (BPC3)
|OA=1
}}

{{omim
|desc=SEX HORMONE-BINDING GLOBULIN; SHBG
|id=182205
|rsnum=1799941
}}
{{PMID Auto
|PMID=19679209
|Title=Effects of Polymorphisms of the Sex Hormone-Binding Globulin (SHBG) Gene on Free Estradiol and Bone Mineral Density
|OA=1
}}

{{PMID Auto
|PMID=19933169
|Title=Genetic evidence that raised Sex Hormone Binding Globulin (SHBG) levels reduce the risk of type 2 diabetes
|OA=1
}}

{{omim
|id=613498
|rsnum=1799941
}}

{{PMID Auto
|PMID=16926255
|Title=SHBG gene promoter polymorphisms in men are associated with serum sex hormone-binding globulin, androgen and androgen metabolite levels, and hip bone mineral density.
}}

{{PMID Auto
|PMID=17411440
|Title=Ovarian cancer risk and common variation in the sex hormone-binding globulin gene: a population-based case-control study.
|OA=1
}}

{{PMID Auto
|PMID=18464913
|Title=A genome-wide association study identifies protein quantitative trait loci (pQTLs).
|OA=1
}}

{{PMID Auto
|PMID=18628428
|Title=Polymorphisms in genes involved in sex hormone metabolism, estrogen plus progestin hormone therapy use, and risk of postmenopausal breast cancer.
|OA=1
}}

{{PMID Auto
|PMID=18980759
|Title=Polymorphisms of estrogen-related genes jointly confer susceptibility to human spermatogenic defect.
}}

{{PMID Auto
|PMID=19064566
|Title=Identification of common variants in the SHBG gene affecting sex hormone-binding globulin levels and breast cancer risk in postmenopausal women.
|OA=1
}}

{{PMID Auto
|PMID=19091090
|Title=Genetic polymorphisms are associated with serum levels of sex hormone binding globulin in postmenopausal women.
|OA=1
}}

{{PMID Auto
|PMID=20616999
|Title=Usefulness of Mendelian randomization in observational epidemiology.
|OA=1
}}

{{PMID Auto
|PMID=20841609
|Title=Relationships of circulating sex hormone-binding globulin with metabolic traits in humans.
|OA=1
}}

{{PMID Auto
|PMID=21252242
|Title=Polymorphisms in the SHBG gene influence serum SHBG levels in women with polycystic ovary syndrome.
|OA=1
}}

{{PMID Auto
|PMID=21283750
|Title=Studies of the association of Arg72Pro of tumor suppressor protein p53 with type 2 diabetes in a combined analysis of 55,521 Europeans.
|OA=1
}}

{{PMID Auto
|PMID=21429951
|Title=Quantitative trait analysis suggests polymorphisms of estrogen-related genes regulate human sperm concentrations and motility.
}}

[[Sex Hormone Regulation]]

{{PMID Auto
|PMID=24327369
|Title=Single-nucleotide polymorphism, rs1799941 in the sex hormone-binding globulin (SHBG) gene, related to both serum testosterone and SHBG levels and the risk of myocardial infarction, type 2 diabetes, cancer and mortality in men: the Tromsø Study
}}

{{PMID Auto
|PMID=22936694
|Title=Genome-wide association study identifies a new locus JMJD1C at 10q21 that may influence serum androgen levels in men.
|OA=1
}}

{{PMID Auto
|PMID=23001781
|Title=Common variants in the sex hormone-binding globulin gene (SHBG) and polycystic ovary syndrome (PCOS) in Mediterranean women.
}}

{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}