{{Rsnum
|rsid=1799946
|Gene=DEFB1
|Chromosome=8
|position=6877909
|Orientation=minus
|GMAF=0.4219
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=DEFB1
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 14.2 | 44.2 | 41.6
| HCB | 18.2 | 54.0 | 27.7
| JPT | 26.8 | 50.9 | 22.3
| YRI | 36.7 | 49.0 | 14.3
| ASW | 15.8 | 70.2 | 14.0
| CHB | 18.2 | 54.0 | 27.7
| CHD | 25.7 | 47.7 | 26.6
| GIH | 20.0 | 52.0 | 28.0
| LWK | 24.5 | 51.8 | 23.6
| MEX | 7.0 | 40.4 | 52.6
| MKK | 26.9 | 57.7 | 15.4
| TSI | 20.6 | 46.1 | 33.3
| HapMapRevision=28
}}{{PMID|17943629}} found no association with [[Crohn's disease]] for [[rs1799946]], but did find associations for two other [[DEFB1]] SNPs, [[rs11362]] and [[rs1800972]].

{{ neighbor
| rsid = 1800972
| distance = 8
}}

{{PMID Auto
|PMID=20618470
|Title=Beta defensin-1 gene (DEFB1) polymorphisms are not associated with atopic dermatitis in children and adolescents from northeast Brazil (Recife, Pernambuco)
}}

{{PMID Auto
|PMID=16700921
|Title=Contribution of alpha- and beta-defensins to lung function decline and infection in smokers: an association study.
|OA=1
}}

{{PMID Auto
|PMID=18396467
|Title=Genetic variation and haplotype structures of innate immunity genes in eastern India.
|OA=1
}}

{{PMID Auto
|PMID=18938660
|Title=Association of beta-defensin 1 single nucleotide polymorphisms with Crohn's disease.
}}

{{PMID Auto
|PMID=18991164
|Title=Potential role of human beta-defensin 1 in Helicobacter pylori-induced gastritis.
}}

{{PMID Auto
|PMID=19390326
|Title=Role of beta-defensin-1 polymorphisms in mother-to-child transmission of HIV-1.
}}

{{PMID Auto
|PMID=19712472
|Title=Association of a genetic polymorphism (-44 C/G SNP) in the human DEFB1 gene with expression and inducibility of multiple beta-defensins in gingival keratinocytes.
|OA=1
}}

{{PMID Auto
|PMID=20041166
|Title=Common genetic variation and the control of HIV-1 in humans.
|OA=1
}}

{{PMID Auto
|PMID=22384213
|Title=Genetic variability in beta-defensins is not associated with susceptibility to Staphylococcus aureus bacteremia.
|OA=1
}}

{{PMID Auto
|PMID=22809755
|Title=Immune defense single nucleotide polymorphisms and recruitment strategies associated with contact lens keratitis
}}

{{PMID Auto
|PMID=23204181
|Title=Impaired beta-defensin expression in human skin links DEFB1 promoter polymorphisms with persistent Staphylococcus aureus nasal carriage.
}}

{{PMID Auto
|PMID=25020984
|Title=8.4 Serum beta defensin concentration in the first trimester is related to genotype, and is higher in women who develop PPROM and deliver before 34 weeks
}}

{{PMID Auto
|PMID=25083086
|Title=Relevance of α-defensins (HNP1-3) and defensin β-1 in diabetes
}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}