{{Rsnum
|rsid=1800435
|Gene=ALAD
|Chromosome=9
|position=113391611
|Orientation=minus
|ReferenceAllele=G
|MissenseAllele=C
|GMAF=0.04683
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;G)
|geno3=(G;G)
|Gene_s=ALAD
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;G)
| geno3=(G;G)
| CEU | 0.0 | 0.0 | 0.0
| HCB | 0.0 | 0.0 | 0.0
| JPT | 0.0 | 0.0 | 0.0
| YRI | 0.0 | 0.0 | 100.0
| ASW | 0.0 | 0.0 | 0.0
| CHB | 0.0 | 0.0 | 0.0
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 0.0 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}{{omim
|desc=AMINOLEVULINATE DEHYDRATASE, ALAD*1/ALAD*2 POLYMORPHISM
|id=125270
|rsnum=1800435
|variant=0003
}}

{{PMID Auto
|PMID=19686844
|Title=Lead and cognitive function in ALAD genotypes in the third National Health and Nutrition Examination Survey
}}

{{ClinVar
|rsid=1800435
|Reversed=1
|FwdREF=G
|FwdALT=C
|REF=C
|ALT=G
|RSPOS=116153891
|CHROM=9
|GMAF=0.0467
|dbSNPBuildID=89
|SSR=0
|SAO=1
|VP=0x050368000000150517110100
|GENEINFO=ALAD:210
|GENE_NAME=ALAD
|GENE_ID=210
|WGT=0
|VC=SNV
|CLNALLE=1
|CLNHGVS=NC_000009.11:g.116153891C>G
|CLNORIGIN=1
|CLNSIG=2
|Tags=RV;PM;PMC;S3D;SLO;VLD;G5;HD;GNO;KGPhase1;KGPROD;OTHERKG;PH3;LSD;OM
|CAF=0.9532; 0.04683
|CLNACC=RCV000018360.1
|CLNDBN=AMINOLEVULINATE DEHYDRATASE, ALAD*1/ALAD*2 POLYMORPHISM
|CLNSRC=OMIM Allelic Variant
|CLNSRCID=125270.0003
|COMMON=1
|Disease=AMINOLEVULINATE DEHYDRATASE
}}

{{PMID Auto
|PMID=18569569
|Title=Lack of association of delta-aminolevulinate dehydratase polymorphisms with blood lead levels and hemoglobin in Romanian women from a lead-contaminated region.
}}

{{PMID Auto
|PMID=18639233
|Title=An association analysis of murine anxiety genes in humans implicates novel candidate genes for anxiety disorders.
|OA=1
}}

{{PMID Auto
|PMID=18936436
|Title=Prevalence in the United States of selected candidate gene variants: Third National Health and Nutrition Examination Survey, 1991-1994.
|OA=1
}}

{{PMID Auto
|PMID=19165391
|Title=Iron metabolism genes, low-level lead exposure, and QT interval.
|OA=1
}}

{{PMID Auto
|PMID=20798009
|Title=Comparison of occupational exposure assessment methods in a case-control study of lead, genetic susceptibility and risk of adult brain tumours.
|OA=1
}}

{{PMID Auto
|PMID=21439310
|Title=delta-Aminolevulinic acid dehydratase genotype predicts toxic effects of lead on workers' peripheral nervous system.
}}

{{GET Evidence
|gene=ALAD
|aa_change=Lys68Asn
|aa_change_short=K68N
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs1800435
|overall_frequency_n=7
|overall_frequency_d=128
|overall_frequency=0.0546875
|n_genomes=7
|n_genomes_annotated=0
|n_haplomes=7
|n_articles=0
|n_articles_annotated=0
|gene_in_genetests=Y
|genetests_testable=Y
|nblosum100=1
|autoscore=1
|webscore=N
}}

{{PMID Auto
|PMID=24156693
|Title=Influence of delta-aminolevulinic Acid dehydratase gene polymorphism on selected lead exposure biomarkers in a cohort of ex-smelter workers
}}

{{PMID Auto
|PMID=22925625
|Title=Inverse association of intellectual function with very low blood lead but not with manganese exposure in Italian adolescents.
|OA=1
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}