{{Rsnum
|rsid=1800449
|Gene=LOX
|Chromosome=5
|position=122077513
|Orientation=plus
|ReferenceAllele=G
|MissenseAllele=A
|GMAF=0.1667
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=LOX
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 2.7 | 27.7 | 69.6
| HCB | 5.1 | 27.7 | 67.2
| JPT | 4.5 | 25.0 | 70.5
| YRI | 0.7 | 20.4 | 78.9
| ASW | 0.0 | 33.3 | 66.7
| CHB | 5.1 | 27.7 | 67.2
| CHD | 6.4 | 37.6 | 56.0
| GIH | 0.0 | 21.8 | 78.2
| LWK | 3.6 | 27.3 | 69.1
| MEX | 1.7 | 29.3 | 69.0
| MKK | 5.8 | 22.6 | 71.6
| TSI | 7.8 | 23.5 | 68.6
| HapMapRevision=28
}}
{{omim
|desc=LYSYL OXIDASE POLYMORPHISM
|id=153455
|rsnum=1800449
|variant=0001
}}

{{PMID Auto
|PMID=19654310
|Title=A Loss-of-Function Polymorphism in the Propeptide Domain of the LOX Gene and Breast Cancer
|OA=1
}}

{{PMID Auto
|PMID=20929399
|Title=Lysyl Oxidase 473 G&amp;gt;A Polymorphism and Breast Cancer Susceptibility in Chinese Han Population
}}

{{PMID Auto
|PMID=22533780
|Title=Lysyl Oxidase G473A Polymorphism Is Associated with Increased Risk of Ovarian Cancer
}}

{{PMID Auto
|PMID=22661479
|Title=Variation in the Lysyl Oxidase (LOX) Gene Is Associated with Keratoconus in Family-Based and Case-Control Studies
|OA=1
}}

{{ClinVar
|rsid=1800449
|Reversed=1
|FwdREF=G
|FwdALT=A
|REF=C
|ALT=T
|RSPOS=121413208
|CHROM=5
|GMAF=0.1662
|dbSNPBuildID=89
|SSR=0
|SAO=1
|VP=0x050168000000170517110100
|GENEINFO=LOX:4015
|GENE_NAME=LOX
|GENE_ID=4015
|WGT=0
|VC=SNV
|CLNALLE=1
|CLNHGVS=NC_000005.9:g.121413208C>T
|CLNORIGIN=1
|CLNSIG=2
|Tags=RV;PM;PMC;SLO;VLD;G5A;G5;HD;GNO;KGPhase1;KGPROD;OTHERKG;PH3;LSD;OM
|CAF=0.8333; 0.1667
|CLNACC=RCV000015437.1
|CLNDBN=LYSYL OXIDASE POLYMORPHISM
|CLNSRC=OMIM Allelic Variant
|CLNSRCID=153455.0001
|COMMON=1
|Disease=LYSYL OXIDASE POLYMORPHISM
}}

{{PMID|21995629}} Lysyl oxidase G473A polymorphism is closely associated with susceptibility to gastric cancer in a South Korean population.

{{GET Evidence
|gene=LOX
|aa_change=Arg158Gln
|aa_change_short=R158Q
|impact=benign
|qualified_impact=Insufficiently evaluated benign
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs1800449
|overall_frequency_n=1853
|overall_frequency_d=10742
|overall_frequency=0.1725
|n_genomes=12
|n_genomes_annotated=0
|n_haplomes=13
|n_articles=0
|n_articles_annotated=0
|qualityscore_in_silico=1
|qualitycomment_in_silico=Y
|in_omim=Y
|pph2_score=0.992
|nblosum100=0
|autoscore=3
|webscore=N
}}

{{PMID Auto
|PMID=22722997
|Title=Lysyl oxidase polymorphisms and ischemic stroke--a case control study.
}}

{{PMID Auto
|PMID=25141126
|Title=Association of the G473A Polymorphism and Expression of Lysyl Oxidase with Breast Cancer Risk and Survival in European Women: A Hospital-Based Case-Control Study
}}
{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}