{{Rsnum
|rsid=1800559
|Chromosome=1
|Orientation=minus
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene=CACNA1S
|position=201060815
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|Gene_s=CACNA1S
}}{{omim
|id=114208
|rsnum=1800559
|variant=0004
}}

{{ClinVar
|rsid=1800559
|Reversed=1
|FwdREF=G
|FwdALT=A
|REF=C
|ALT=T
|RSPOS=201060815
|CHROM=1
|dbSNPBuildID=89
|SSR=0
|SAO=1
|VP=0x050168000a05000002110100
|GENEINFO=CACNA1S:779
|GENE_NAME=CACNA1S
|GENE_ID=779
|WGT=1
|VC=SNV
|CLNALLE=1
|CLNHGVS=NC_000001.11:g.201060815C>T
|CLNSRC=ClinVar; GeneReviews; OMIM Allelic Variant
|CLNORIGIN=1
|CLNSRCID=NM_000069.2:c.3257G>A; NBK1338; 114208.0004
|CLNSIG=255
|CLNCUI=CN034227; CN031165
|CLNDBN=Malignant hyperthermia susceptibility type 5; Hypokalemic periodic paralysis 1
|Disease=Malignant hyperthermia susceptibility type 5; Hypokalemic periodic paralysis 1
|CLNACC=RCV000019193.1; RCV000020095.1
|Tags=RV;PM;PMC;SLO;NSM;REF;ASP;OTHERKG;LSD;OM
|CLNDSDB=GeneReviews:MedGen:OMIM:Orphanet; GeneReviews:GeneReviews:MedGen:OMIM:Orphanet
|CLNDSDBID=NBK1146:C2930984:601887:ORPHA423; NBK1338:NBK1496:CN031165:170400:ORPHA681
}}

{{PMID|9199552|OA=1
}} Malignant-hyperthermia susceptibility is associated with a mutation of the alpha 1-subunit of the human dihydropyridine-sensitive L-type voltage-dependent calcium-channel receptor in skeletal muscle.

{{PMID|10590402}} Genetics and pathogenesis of malignant hyperthermia.

{{PMID|11260227}} Identification of the Arg1086His mutation in the alpha subunit of the voltage-dependent calcium channel (CACNA1S) in a North American family with malignant hyperthermia.

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}