{{Rsnum
|rsid=1800624
|Gene=AGER
|Chromosome=6
|position=32184610
|Orientation=minus
|GMAF=0.1928
|Gene_s=AGER,PBX2
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;T)
|geno3=(T;T)
|orientation=minus
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;T)
| geno3=(T;T)
| CEU | 1.6 | 25.0 | 73.4
| HCB | 0.0 | 32.6 | 67.4
| JPT | 14.0 | 39.5 | 46.5
| YRI | 0.0 | 1.6 | 98.4
| ASW | 0.0 | 0.0 | 0.0
| CHB | 0.0 | 32.6 | 67.4
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 0.0 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}
[[rs1800624]] (T-374A / -374T>A or A-374T / -374A>T) is a SNP located upstream of the [[AGER]] (Advanced Glycation End product Receptor) gene.

{{PMID|11375354}} mean increase of threefold chloramphenicol acetyl transferase (CAT) reporter gene expression driven by the -738 to +49 RAGE gene fragment containing the -374 A allele

{{PMID Auto
|PMID=20051912
|Title=The association between the -374T/A polymorphism of the receptor for advanced glycation endproducts gene and blood pressure and arterial stiffness is modified by glucose metabolism status: the Hoorn and CoDAM studies
}}

{{PMID Auto
|PMID=20568058
|Title=The functional polymorphisms -429T&gt;C and -374T&gt;A of the RAGE gene promoter are not associated with gestational diabetes in Euro-Brazilians
}}

{{PMID Auto
|PMID=21311028
|Title=The functional -374T/A polymorphism of the receptor for advanced glycation end products (RAGE) may modulate Crohn's disease
}}

{{PMID Auto
|PMID=22133449
|Title=Polymorphisms of the promoter and exon 3 of the receptor for advanced glycation end products (RAGE) in Euro- and Afro-Brazilians
}}

{{PMID Auto
|PMID=18575614
|Title=Association between LTA, TNF and AGER polymorphisms and late diabetic complications.
|OA=1
}}

{{PMID Auto
|PMID=18796298
|Title=Polymorphisms in advanced glycosylation end product-specific receptor (AGER) gene, insulin resistance, and type 2 diabetes mellitus.
}}

{{PMID Auto
|PMID=19587357
|Title=A systematic meta-analysis of genetic association studies for diabetic retinopathy.
|OA=1
}}

{{PMID Auto
|PMID=20353610
|Title=Association analysis of ADPRT1, AKR1B1, RAGE, GFPT2 and PAI-1 gene polymorphisms with chronic renal insufficiency among Asian Indians with type-2 diabetes.
|OA=1
}}

{{PMID Auto
|PMID=21254849
|Title=AGER gene -374T>A (rs1800624) polymorphism is not associated with the severity of non-diabetic coronary artery disease in Han Chinese.
}}

{{PMID Auto
|PMID=22964273
|Title=Association study of polymorphisms in the receptor for advanced glycation end-products (RAGE) gene with susceptibility and prognosis of heart failure
}}

{{PMID Auto
|PMID=24605038
|Title=RAGE gene three polymorphisms with Crohn's disease susceptibility in Chinese Han population
|OA=1
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}