{{Rsnum
|rsid=1800625
|Gene=AGER
|Chromosome=6
|position=32184665
|Orientation=minus
|GMAF=0.1194
|Gene_s=AGER,PBX2
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 2.7 | 25.7 | 71.7
| HCB | 2.2 | 19.9 | 77.9
| JPT | 0.9 | 18.6 | 80.5
| YRI | 4.8 | 23.8 | 71.4
| ASW | 5.4 | 25.0 | 69.6
| CHB | 2.2 | 19.9 | 77.9
| CHD | 0.0 | 18.3 | 81.7
| GIH | 5.0 | 33.7 | 61.4
| LWK | 2.7 | 8.2 | 89.1
| MEX | 0.0 | 17.2 | 82.8
| MKK | 0.0 | 7.8 | 92.2
| TSI | 2.9 | 25.5 | 71.6
| HapMapRevision=28
}}[[rs1800625]] (-429T>C / T-429C) is a SNP located upstream of the [[AGER]] (Advanced Glycation End product Receptor) gene.

{{PMID|11375354}} mean increase of twofold chloramphenicol acetyl transferase (CAT) reporter gene expression driven by the -738 to +49 RAGE gene fragment containing the -429 C allele

{{PMID Auto
|PMID=20568058
|Title=The functional polymorphisms -429T&gt;C and -374T&gt;A of the RAGE gene promoter are not associated with gestational diabetes in Euro-Brazilians
}}

{{PMID Auto
|PMID=21311028
|Title=The functional -374T/A polymorphism of the receptor for advanced glycation end products (RAGE) may modulate Crohn's disease
}}

{{PMID Auto
|PMID=22133449
|Title=Polymorphisms of the promoter and exon 3 of the receptor for advanced glycation end products (RAGE) in Euro- and Afro-Brazilians
}}

{{PMID Auto
|PMID=22827914
|Title=Identification of haplotype tag single nucleotide polymorphisms within the receptor for advanced glycation end products gene and their clinical relevance in patients with major trauma
|OA=1
}}

{{PMID Auto
|PMID=18796298
|Title=Polymorphisms in advanced glycosylation end product-specific receptor (AGER) gene, insulin resistance, and type 2 diabetes mellitus.
}}

{{PMID Auto
|PMID=19587357
|Title=A systematic meta-analysis of genetic association studies for diabetic retinopathy.
|OA=1
}}

{{PMID Auto
|PMID=20353610
|Title=Association analysis of ADPRT1, AKR1B1, RAGE, GFPT2 and PAI-1 gene polymorphisms with chronic renal insufficiency among Asian Indians with type-2 diabetes.
|OA=1
}}

{{PMID Auto
|PMID=21297263
|Title=Genetic association of sequence variants near AGER/NOTCH4 and dementia.
|OA=1
}}

{{PMID Auto
|PMID=22964273
|Title=Association study of polymorphisms in the receptor for advanced glycation end-products (RAGE) gene with susceptibility and prognosis of heart failure
}}

{{PMID Auto
|PMID=24605038
|Title=RAGE gene three polymorphisms with Crohn's disease susceptibility in Chinese Han population
|OA=1
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}