{{Rsnum
|rsid=1800682
|Gene=ACTA2
|Chromosome=10
|position=90749963
|Orientation=minus
|GMAF=0.4761
|Gene_s=ACTA2,FAS
|Assembly=GRCh37.p2
|GenomeBuild=37.2
|dbSNPBuild=134
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
}}
{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 11.5 | 57.5 | 31.0
| HCB | 13.9 | 43.1 | 43.1
| JPT | 29.2 | 41.6 | 29.2
| YRI | 61.9 | 33.3 | 4.8
| ASW | 47.4 | 42.1 | 10.5
| CHB | 13.9 | 43.1 | 43.1
| CHD | 15.7 | 51.9 | 32.4
| GIH | 13.9 | 52.5 | 33.7
| LWK | 60.9 | 30.9 | 8.2
| MEX | 27.6 | 51.7 | 20.7
| MKK | 50.6 | 41.0 | 8.3
| TSI | 15.7 | 61.8 | 22.5
| HapMapRevision=28
}}{{PMID Auto
|PMID=19240174
|Title=Polymorphisms in the FAS and FASL genes and survival of early stage non-small cell lung cancer.
}}

{{PMID Auto
|PMID=18757527
|Title=Apoptosis gene polymorphisms, age, smoking and the risk of non-small cell lung cancer.
|OA=1
}}

{{PMID Auto
|PMID=18759263
|Title=Features associated with, and the impact of, hemolytic anemia in patients with systemic lupus erythematosus: LX, results from a multiethnic cohort.
|OA=1
}}

{{PMID Auto
|PMID=18805939
|Title=Functional genetic polymorphisms and female reproductive disorders: part II--endometriosis.
|OA=1
}}

{{PMID Auto
|PMID=18854777
|Title=Germline genetic variations in drug action pathways predict clinical outcomes in advanced lung cancer treated with platinum-based chemotherapy.
|OA=1
}}

{{PMID Auto
|PMID=19542541
|Title=Polymorphisms in cell death pathway genes are associated with altered sperm apoptosis and poor semen quality.
}}

{{PMID Auto
|PMID=19669200
|Title=Analysis of single nucleotide polymorphisms in the FAS and CTLA-4 genes of peripheral T-cell lymphomas.
|OA=1
}}

{{PMID Auto
|PMID=19941645
|Title=Fas and FasL gene polymorphisms are not associated with cervical cancer but differ among Black and Mixed-ancestry South Africans.
|OA=1
}}

{{PMID Auto
|PMID=20438363
|Title=Fas and FasL polymorphisms are not associated with acute myeloid leukemia risk in Koreans.
}}

{{PMID Auto
|PMID=21926110
|Title=Population-specific genetic associations with oesophageal squamous cell carcinoma in South Africa.
|OA=1
}}

{{PMID Auto
|PMID=23141929
|Title=A Controlled Case Study of the Relationship Between Environmental Risk Factors and Apoptotic Gene Polymorphism and Lumbar Disc Herniation
}}

{{PMID Auto
|PMID=23392773
|Title=Apoptosis-related Fas and FasL gene polymorphisms' associations with knee osteoarthritis
}}

{{PMID Auto
|PMID=22775001
|Title=Polymorphisms in Fas gene is associated with HIV-related lipoatrophy in Thai patients
|OA=1
}}

{{PMID Auto
|PMID=23961418
|Title=Association of the HLA locus and TNF with type I autoimmune hepatitis susceptibility in New Zealand Caucasians
|OA=1
}}

{{PMID Auto
|PMID=24114012
|Title=CD95 rs1800682 polymorphism and cervical cancer risk: evidence from a meta-analysis
}}

{{PMID Auto
|PMID=24424626
|Title=Association of genetic variants in apoptosis genes FAS and FASL with radiation-induced late toxicity after prostate cancer radiotherapy
}}

{{PMID Auto
|PMID=23065220
|Title=Association of Fas gene polymorphisms with systemic lupus erythematosus: a meta-analysis.
}}

{{PMID Auto
|PMID=23749041
|Title=Relation of the Fas and FasL gene polymorphisms with susceptibility to and severity of rheumatoid arthritis.
}}

{{PMID Auto
|PMID=24800976
|Title=Fas -670A/G (rs1800682) Polymorphism and Digestive Cancer Risk in Asians: A Meta-Analysis
}}

{{PMID Auto GWAS
  |PMID=24292274
  |Trait=Chronic lymphocytic leukemia
  |Title=A genome-wide association study identifies multiple susceptibility loci for chronic lymphocytic leukemia.
  |RiskAllele=A
  |Pval=2E-8
  |OR=1.25
  |ORtxt=[NR]
  }}

{{PMID Auto
|PMID=25085585
|Title=Significant association among the Fas -670 A/G (rs1800682) polymorphism and esophageal cancer, hepatocellular carcinoma, and prostate cancer susceptibility: a meta-analysis
}}

{{PMID Auto
|PMID=24448373
|Title=Association of specific diplotypes defined by common rs1800682 and rare rs34995925 single nucleotide polymorphisms within the STAT1 transcription binding site of the FAS gene promoter with preeclampsia
}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}