{{Rsnum
|rsid=1800764
|Gene=ANAPC16
|Chromosome=17
|position=63473168
|Orientation=plus
|GMAF=0.4803
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 20.4 | 45.1 | 34.5
| HCB | 11.0 | 39.7 | 49.3
| JPT | 18.6 | 52.2 | 29.2
| YRI | 87.8 | 12.2 | 0.0
| ASW | 68.4 | 26.3 | 5.3
| CHB | 11.0 | 39.7 | 49.3
| CHD | 11.9 | 55.0 | 33.0
| GIH | 17.8 | 54.5 | 27.7
| LWK | 80.7 | 17.4 | 1.8
| MEX | 14.0 | 36.8 | 49.1
| MKK | 68.6 | 28.8 | 2.6
| TSI | 27.7 | 45.5 | 26.7
| HapMapRevision=28
}}{{PMID Auto
|PMID=19956428
|Title=Angiotensin-converting enzyme levels and activity in Alzheimer's disease: differences in brain and CSF ACE and association with ACE1 genotypes
|OA=1
}}

{{PMID|17376814}} The C allele may be associated with an increased risk for [[diabetic nephropathy]].

{{PMID Auto
|PMID=19787680
|Title=Identification of specific angiotensin-converting enzyme variants and haplotypes that confer risk and protection against type 2 diabetic nephropathy
}}

{{PMID Auto
|PMID=15793268
|Title=Genetic variation at the ACE gene is associated with persistent microalbuminuria and severe nephropathy in type 1 diabetes: the DCCT/EDIC Genetics Study.
|OA=1
}}

{{PMID Auto
|PMID=17092869
|Title=Haplotype structure of five SNPs within the ACE gene in the Tunisian population.
}}

{{PMID Auto
|PMID=18813964
|Title=Alzheimer's disease risk variants show association with cerebrospinal fluid amyloid beta.
|OA=1
}}

{{PMID Auto
|PMID=18830724
|Title=Assessment of Alzheimer's disease case-control associations using family-based methods.
|OA=1
}}

{{PMID Auto
|PMID=19963597
|Title=Visual exploration of genetic association with voxel-based imaging phenotypes in an MCI/AD study.
|OA=1
}}

{{PMID Auto
|PMID=20574532
|Title=Intermediate phenotypes identify divergent pathways to Alzheimer's disease.
|OA=1
}}

{{PMID Auto
|PMID=20625269
|Title=Amyloid-beta-Related Genes SORL1 and ACE are Genetically Associated With Risk for Late-onset Alzheimer Disease in the Chinese Population.
}}

{{PMID Auto
|PMID=20682755
|Title=A pilot study of gene/gene and gene/environment interactions in Alzheimer disease.
|OA=1
}}

{{PMID Auto
|PMID=21297258
|Title=A multi-center study of ACE and the risk of late-onset Alzheimer's disease.
|OA=1
}}

{{PMID Auto
|PMID=22908855
|Title=The linkage disequilibrium pattern of the angiotensin converting enzyme gene in Arabic and Asian population groups
}}

{{PMID Auto
|PMID=24851853
|Title=Angiotensin-converting enzyme gene polymorphisms and risk for sporadic Alzheimer's disease: a meta-analysis
}}

{{PMID Auto
|PMID=24863667
|Title=Influence of Alzheimer's disease genes on cognitive decline: the Guangzhou Biobank Cohort Study
}}
{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}