{{Rsnum
|rsid=1800775
|Gene=CETP
|Chromosome=16
|position=56961324
|Orientation=plus
|GMAF=0.4844
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;C)
|geno3=(C;C)
|Gene_s=CETP
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;C)
| geno3=(C;C)
| CEU | 25.7 | 51.3 | 23.0
| HCB | 24.6 | 54.5 | 20.9
| JPT | 28.4 | 50.5 | 21.1
| YRI | 35.9 | 46.9 | 17.2
| ASW | 26.3 | 49.1 | 24.6
| CHB | 24.6 | 54.5 | 20.9
| CHD | 26.2 | 53.3 | 20.6
| GIH | 37.0 | 51.0 | 12.0
| LWK | 41.1 | 42.1 | 16.8
| MEX | 31.0 | 50.0 | 19.0
| MKK | 31.6 | 45.2 | 23.2
| TSI | 26.7 | 45.5 | 27.7
| HapMapRevision=28
}}
{{PMID|19263529|OA=1
}} [[rs1799864]](G), [[rs3025058]](A) and [[rs662]] were associated with increased risk, and [[rs1800775]](A) with reduced risk of recurrent [[venous thromboembolism]]
{{Report GE
|PubMed=17463246
|Source=lit
|AffyProbeset=SNP_A-2182111
|AffyOrientation=same
|AlleleA=A
|AlleleB=C
|onGW5=0
|rsid=1800775
|ancestral=A
|RiskPopulation=NEU
|RiskAllele=C
|CaseFreq=
|ControlFreq=0.44
|OddsRatioHet=
|OddsRatioHom=
|OddsRatioAll=-
|Disease=Elevated Apolipoprotein A1
|DiseaseSymbol=E-APOA1
}}

{{PMID Auto GWAS
|PMID=18193044
|Trait=HDL cholesterol
|Title=Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans
|RiskAllele=C
|Pval=1E-73
|OR=0.18
|ORtxt=[0.16-0.20]% SD lower
|OA=1
}}
{{PMID Auto
|PMID=19435741
|Title=Common lipid-altering gene variants are associated with therapeutic intervention thresholds of lipid levels in older people
|OA=1
}}

{{omim
|desc=CHOLESTERYL ESTER TRANSFER PROTEIN, PLASMA; CETP
|id=118470
|rsnum=1800775
}}

{{omim
|desc=HIGH DENSITY LIPOPROTEIN CHOLESTEROL LEVEL QUANTITATIVE TRAIT LOCUS
|id=612797
|rsnum=1800775
}}

{{PharmGKB
|RSID=rs1800775
|Name_s=CETP:-629C>A
|Gene_s=CETP
|Feature=NA
|Evidence=PubMed ID:18560005
|Annotation=Meta-analysis showed weak inverse association with coronary risk for the CETP:-629C>A, A allele.
|Drugs=
|Drug Classes=
|Diseases=Coronary Disease
|Curation Level=Curated
|PharmGKB Accession ID=PA162361025
}}
{{PMID Auto GWAS
|PMID=20031564
|Trait=HDL cholesterol
|Title=Polymorphism in the CETP Gene Region, HDL Cholesterol, and Risk of Future Myocardial Infarction: Genomewide Analysis Among 18 245 Initially Healthy Women From the Women's Genome Health Study
|RiskAllele=A
|Pval=4E-93
|OR=3.09
|ORtxt=mg/dL increase
|OA=1
}}

{{PMID Auto
|PMID=19773416
|Title=A gene score of nine LDL and HDL regulating genes is associated with fluvastatin-induced cholesterol changes in women
|OA=1
}}
{{PMID Auto
|PMID=21185205
|Title=The relationship of ACE and CETP gene polymorphisms with cardiovascular disease in a cohort of Asian Indian patients with and those without type 2 diabetes
}}

{{PMID Auto
|PMID=12434007
|Title=SNP genotyping on a genome-wide amplified DOP-PCR template.
|OA=1
}}

{{PMID Auto
|PMID=12475937
|Title=Association testing by DNA pooling: an effective initial screen.
|OA=1
}}

{{PMID Auto
|PMID=17903299
|Title=A genome-wide association study for blood lipid phenotypes in the Framingham Heart Study.
|OA=1
}}

{{PMID Auto
|PMID=18513389
|Title=New application of intelligent agents in sporadic amyotrophic lateral sclerosis identifies unexpected specific genetic background.
|OA=1
}}

{{PMID Auto
|PMID=18549840
|Title=Cholesterol ester transfer protein, interleukin-8, peroxisome proliferator activator receptor alpha, and Toll-like receptor 4 genetic variations and risk of incident nonfatal myocardial infarction and ischemic stroke.
|OA=1
}}

{{PMID Auto
|PMID=18637884
|Title=Cholesteryl ester transfer protein (CETP) genetic variation and early onset of non-fatal myocardial infarction.
|OA=1
}}

{{PMID Auto
|PMID=19041386
|Title=Genetic-epidemiological evidence on genes associated with HDL cholesterol levels: a systematic in-depth review.
|OA=1
}}

{{PMID Auto
|PMID=19060910
|Title=Genome-wide association analysis of metabolic traits in a birth cohort from a founder population.
|OA=1
}}

{{PMID Auto
|PMID=19131662
|Title=A meta-analysis of candidate gene polymorphisms and ischemic stroke in 6 study populations: association of lymphotoxin-alpha in nonhypertensive patients.
|OA=1
}}

{{PMID Auto
|PMID=19185284
|Title=Common variation in the beta-carotene 15,15'-monooxygenase 1 gene affects circulating levels of carotenoids: a genome-wide association study.
|OA=1
}}

{{PMID Auto
|PMID=19197348
|Title=Genome-wide association studies in an isolated founder population from the Pacific Island of Kosrae.
|OA=1
}}

{{PMID Auto
|PMID=19951432
|Title=Analysis of recently identified dyslipidemia alleles reveals two loci that contribute to risk for carotid artery disease.
|OA=1
}}

{{PMID Auto
|PMID=20018036
|Title=Using a latent growth curve model for an integrative assessment of the effects of genetic and environmental factors on multiple phenotypes.
|OA=1
}}

{{PMID Auto
|PMID=20205905
|Title=Association of repeatedly measured intermediate risk factors for complex diseases with high dimensional SNP data.
|OA=1
}}

{{PMID Auto
|PMID=20370913
|Title=Genome-wide association analysis of total cholesterol and high-density lipoprotein cholesterol levels using the Framingham heart study data.
|OA=1
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs1800775
|overall_frequency_n=2285
|overall_frequency_d=4576
|overall_frequency=0.499344
|n_genomes=48
|n_genomes_annotated=0
|n_haplomes=64
|n_articles=1
|n_articles_annotated=0
|in_gwas=Y
|in_pharmgkb=Y
|autoscore=2
|webscore=N
}}

{{PMID Auto
|PMID=23351584
|Title=Common variation in cholesteryl ester transfer protein: relationship of first major adverse cardiovascular events with the apolipoprotein B/apolipoprotein A-I ratio and the total cholesterol/high-density lipoprotein cholesterol ratio
}}

{{PMID Auto
|PMID=24283500
|Title=CETP gene polymorphisms and risk of coronary atherosclerosis in a Chinese population
}}

{{PMID Auto
|PMID=22715478
|Title=Genotypes associated with lipid metabolism contribute to differences in serum lipid profile of GH-deficient adults before and after GH replacement therapy.
}}

{{PMID Auto
|PMID=23675527
|Title=The association of common SNPs and haplotypes in CETP gene with HDL cholesterol levels in Latvian population.
|OA=1
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | Affy500k}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}