{{Rsnum
|rsid=1800787
|Gene=FGB
|Chromosome=4
|position=154562863
|Orientation=plus
|GMAF=0.1763
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=FGB
}}[[rs1800787(T;T)]] homozygotes are at 6 fold higher risk compared to (C;C) homozygotes or (C;T) heterozygotes for carotid atherosclerosis {{PMID|9514419}}. This polymorphism is known as the "C148-T" variant, and is located in at the "-148" position of the [[FGB]] gene, also known as beta fibrinogen.

{{PMID|18726528}} A meta-analysis of 7 studies did not find a significant association between the -148C/T [[FGB]] SNP and susceptibility to [[coronary artery disease]] in Chinese populations.

Note: due to inconsistencies between databases and the literature, the association of this rs# with this polymorphism name as published is highly likely but not guaranteed.

{{PMID Auto
|PMID=20167083
|Title=Fibrinogen beta variants confer protection against coronary artery disease in a Greek case-control study
|OA=1
}}
{{PMID Auto
|PMID=20978265
|Title=Association of genomic loci from a cardiovascular gene SNP array with fibrinogen levels in European Americans and African-Americans from six cohort studies: the Candidate gene Association Resource (CARe)
|OA=1
}}

{{PMID Auto
|PMID=22386478
|Title=Fibrinogen polymorphisms associated with sporadic cerebral hemorrhage in a Chinese population
}}

{{PMID Auto
|PMID=18239642
|Title=Modifying effects of IL-6 polymorphisms on body size-associated breast cancer risk.
|OA=1
}}

{{PMID Auto
|PMID=19272152
|Title=IL6 and CRP haplotypes are associated with COPD risk and systemic inflammation: a case-control study.
|OA=1
}}

{{PMID Auto
|PMID=20031576
|Title=Association of novel genetic Loci with circulating fibrinogen levels: a genome-wide association study in 6 population-based cohorts.
|OA=1
}}

{{PMID Auto
|PMID=23274712
|Title=Genetic polymorphisms and the risk of myocardial infarction in patients under 45 years of age.
|OA=1
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}