{{Rsnum
|rsid=1800925
|Gene=IL13
|Chromosome=5
|position=132657117
|Orientation=plus
|GMAF=0.2406
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=IL13
}}[[asthma]] related {{PMID|17561245}}

This SNP is in the promoter region of the IL-13 gene

[http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=ShowDetailView&TermToSearch=17615386&ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum PMID: 17615386] IL-13 is involved in pulmonary inflammation, remodeling and susceptibility to [[chronic obstructive pulmonary disease]] (COPD).
This IL13 promoter polymorphism may modulate the adverse effects of cigarette smoking on pulmonary function in long-term cigarette smokers.
Every 20 pack-year increment in smoking was associated with a 2.4% reduction in mean ppFEV1(forced expiratory volume in 1 second, a measure used to assess lung disease, like COPD) in the common homozygous (CC) or heterozygous (CT) promoter genotypes, and an 8.2% reduction in mean ppFEV1 in minor allele homozygotes (TT, recessive model).
*pack-year= packs per day x years smoked

{{PMID|18614543|OA=1
}} [[rs1800925]] and/or [[rs11568506]] related to [[psoriasis]] and/or [[Crohn's disease]] ?

{{PMID|18273035}} [[rs324013]] and [[rs1800925]] influence transcription factor binding. These results are consistent with the Th2 cytokine pathway enhancing resistance to schistosome infection.

{{PMID Auto
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}}
{{PMID|19840389|OA=1
}} Identification of a haplotype block in the 5q31 cytokine gene cluster associated with the susceptibility to severe [[malaria]] 

{{PMID Auto
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}}
{{PMID Auto
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{{PMID Auto
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}}
{{PMID Auto
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{{PMID Auto
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{{PMID Auto
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}}

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{{PMID Auto
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{{PMID Auto
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{{PMID Auto
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{{PMID Auto
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{{PMID Auto
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{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}