{{Rsnum
|rsid=1801058
|Gene=GRK4
|Chromosome=4
|position=3037423
|Orientation=plus
|GMAF=0.3618
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=GRK4
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 38.1 | 44.2 | 17.7
| HCB | 22.8 | 50.0 | 27.2
| JPT | 21.2 | 51.3 | 27.4
| YRI | 81.6 | 17.0 | 1.4
| ASW | 80.4 | 19.6 | 0.0
| CHB | 22.8 | 50.0 | 27.2
| CHD | 19.3 | 53.2 | 27.5
| GIH | 60.4 | 35.6 | 4.0
| LWK | 89.1 | 10.9 | 0.0
| MEX | 39.7 | 44.8 | 15.5
| MKK | 82.4 | 16.3 | 1.3
| TSI | 39.2 | 39.2 | 21.6
| HapMapRevision=28
}}{{PMID Auto
|PMID=20448640
|Title=G protein-coupled receptor kinase 4 gene variants are not associated with preeclampsia in Northern Han Chinese
}}

{{PMID Auto
|PMID=22639547
|Title=Pooled Analyses of the Associations of Polymorphisms in the GRK4 and EMILIN1 Genes with Hypertension Risk
|OA=1
}}

{{PMID Auto
|PMID=19119263
|Title=G-protein-coupled receptor kinase 4 polymorphisms and blood pressure response to metoprolol among African Americans: sex-specificity and interactions.
|OA=1
}}

{{GET Evidence
|gene=GRK4
|aa_change=Val486Ala
|aa_change_short=V486A
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs1801058
|overall_frequency_n=7331
|overall_frequency_d=10758
|overall_frequency=0.681446
|n_genomes=46
|n_genomes_annotated=0
|n_haplomes=71
|n_articles=0
|n_articles_annotated=0
|nblosum100=2
|autoscore=0
|webscore=N
}}

{{PMID Auto
|PMID=22949529
|Title=G protein receptor kinase 4 polymorphisms: beta-blocker pharmacogenetics and treatment-related outcomes in hypertension.
|OA=1
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}