{{Rsnum
|rsid=1801123
|Gene=IRS1
|Chromosome=2
|position=226796327
|Orientation=minus
|GMAF=0.2332
|Gene_s=IRS1
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 85.8 | 14.2 | 0.0
| HCB | 62.0 | 31.4 | 6.6
| JPT | 47.8 | 44.2 | 8.0
| YRI | 27.9 | 51.0 | 21.1
| ASW | 36.8 | 50.9 | 12.3
| CHB | 62.0 | 31.4 | 6.6
| CHD | 64.2 | 31.2 | 4.6
| GIH | 47.5 | 41.6 | 10.9
| LWK | 23.6 | 52.7 | 23.6
| MEX | 55.2 | 41.4 | 3.4
| MKK | 34.6 | 50.6 | 14.7
| TSI | 74.5 | 21.6 | 3.9
| HapMapRevision=28
}}{{PMID Auto
|PMID=22729394
|Title=A non-synonymous polymorphism in IRS1 modifies risk of developing breast and ovarian cancers in BRCA1 and ovarian cancer in BRCA2 mutation carriers
|OA=1
}}

{{PMID|19843326|OA=1
}} Genetic variation in insulin-like growth factor signaling genes and breast cancer risk among BRCA1 and BRCA2 carriers.

{{PMID|19956100|OA=1
}} No association of the IRS1 and PAX4 genes with type I diabetes.

{{PMID|19956101|OA=1
}} Overview of the Rapid Response data.

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | Illumina Human 1M}}