{{Rsnum
|rsid=1801177
|Gene=LPL
|Chromosome=8
|position=19948197
|Orientation=plus
|GMAF=0.01423
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=LPL
}}{{PMID Auto
|PMID=20429872
|Title=Additive effects of LPL, APOA5 and APOE variant combinations on triglyceride levels and hypertriglyceridemia: results of the ICARIA genetic sub-study
|OA=1
}}

{{omim
|id=609708
|rsnum=1801177
|variant=0035
}}

{{ClinVar
|rsid=1801177
|Reversed=0
|FwdREF=G
|FwdALT=A
|REF=G
|ALT=A
|RSPOS=19805708
|CHROM=8
|GMAF=0.0142
|dbSNPBuildID=89
|SSR=0
|SAO=1
|VP=0x05026800000014051e110100
|GENEINFO=LPL:4023
|GENE_NAME=LPL
|GENE_ID=4023
|WGT=0
|VC=SNV
|CLNALLE=1
|CLNHGVS=NC_000008.10:g.19805708G>A
|CLNSRC=OMIM Allelic Variant
|CLNORIGIN=1
|CLNSRCID=609708.0035
|CLNSIG=5
|CLNCUI=C0020474
|CLNDBN=Hyperlipidemia, familial combined
|Disease=Hyperlipidemia
|CLNACC=RCV000001617.1
|Tags=PM;PMC;S3D;VLD;HD;GNO;KGPhase1;KGPilot123;KGPROD;OTHERKG;LSD;OM
|CAF=0.9858; 0.01423
|CLNDSDB=MedGen:OMIM
|CLNDSDBID=C0020474:144250
|COMMON=1
}}

{{PMID Auto
|PMID=17357073
|Title=Genetic analysis of 103 candidate genes for coronary artery disease and associated phenotypes in a founder population reveals a new association between endothelin-1 and high-density lipoprotein cholesterol.
|OA=1
}}

{{PMID Auto
|PMID=18513389
|Title=New application of intelligent agents in sporadic amyotrophic lateral sclerosis identifies unexpected specific genetic background.
|OA=1
}}

{{PMID Auto
|PMID=18922999
|Title=Seven lipoprotein lipase gene polymorphisms, lipid fractions, and coronary disease: a HuGE association review and meta-analysis.
}}

{{PMID Auto
|PMID=19041386
|Title=Genetic-epidemiological evidence on genes associated with HDL cholesterol levels: a systematic in-depth review.
|OA=1
}}

{{PMID Auto
|PMID=19131662
|Title=A meta-analysis of candidate gene polymorphisms and ischemic stroke in 6 study populations: association of lymphotoxin-alpha in nonhypertensive patients.
|OA=1
}}

{{PMID Auto
|PMID=20406163
|Title=Fenofibrate and metabolic syndrome.
}}

{{PMID Auto
|PMID=21146168
|Title=LPL polymorphism (D9N) predicts cardiovascular disease risk directly and through interaction with CETP polymorphism (TaqIB) in women with high HDL cholesterol and CRP.
}}

{{PMID Auto
|PMID=22236405
|Title=LPL gene variants affect apoC-III response to combination therapy of statins and fenofibric acid in a randomized clinical trial of individuals with mixed dyslipidemia.
|OA=1
}}

{{GET Evidence
|gene=LPL
|aa_change=Asp36Asn
|aa_change_short=D36N
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs1801177
|overall_frequency_n=303
|overall_frequency_d=10758
|overall_frequency=0.0281651
|n_genomes=2
|n_genomes_annotated=0
|n_haplomes=2
|n_articles=0
|n_articles_annotated=0
|gene_in_genetests=Y
|pph2_score=0.489
|genetests_testable=Y
|genetests_reviewed=Y
|nblosum100=-1
|autoscore=3
|webscore=N
}}

{{on chip | FTDNA2}}
{{on chip | FTDNA}}