{{Rsnum
|rsid=1801426
|Gene=BRCA2
|Chromosome=13
|position=32398747
|Orientation=plus
|ReferenceAllele=A
|MissenseAllele=G
|GMAF=0.04362
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=BRCA2
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 100.0 | 0.0 | 0.0
| HCB | 92.0 | 8.0 | 0.0
| JPT | 96.5 | 3.5 | 0.0
| YRI | 69.4 | 29.3 | 1.4
| ASW | 80.7 | 19.3 | 0.0
| CHB | 92.0 | 8.0 | 0.0
| CHD | 91.7 | 8.3 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 80.9 | 19.1 | 0.0
| MEX | 86.2 | 13.8 | 0.0
| MKK | 95.5 | 3.8 | 0.6
| TSI | 99.0 | 1.0 | 0.0
| HapMapRevision=28
}}

This SNP, a variant in the [[BRCA2]] gene, is 1 of 25 SNPs reported to represent independently minor, but cumulatively significant, increased risk for [[breast cancer]]. {{PMID|17341484}}

For details of all 25 SNPs in this group, along with the two methods used to calculate overall risk estimates for [[breast cancer]], refer to the SNPedia [[breast cancer]] entry.

For this particular SNP, the risk (minor) allele is (G).
{{ neighbor
| rsid = 11571833
| distance = 258
}}

{{ClinVar
|rsid=1801426
|Reversed=0
|FwdREF=A
|FwdALT=G
|REF=A
|ALT=G
|RSPOS=32972884
|CHROM=13
|GMAF=0.0435
|dbSNPBuildID=89
|SSR=0
|SAO=0
|VP=0x05016000000015051f100101
|GENEINFO=BRCA2:675
|GENE_NAME=BRCA2
|GENE_ID=675
|WGT=0
|VC=SNV
|CLNALLE=1
|CLNHGVS=NC_000013.10:g.32972884A>G
|CLNSIG=2
|Tags=PM;SLO;VLD;G5;HD;GNO;KGPhase1;KGPilot123;KGPROD;OTHERKG;PH3;LSD
|CAF=0.9564; 0.04362
|CLNACC=RCV000034426.1
|CLNDBN=not provided
|COMMON=1
|Disease=not provided
}}

{{GET Evidence
|gene=BRCA2
|aa_change=Ile3412Val
|aa_change_short=I3412V
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs1801426
|overall_frequency_n=407
|overall_frequency_d=10758
|overall_frequency=0.0378323
|n_genomes=6
|n_genomes_annotated=0
|n_haplomes=6
|n_articles=0
|n_articles_annotated=0
|gene_in_genetests=Y
|genetests_testable=Y
|genetests_reviewed=Y
|nblosum100=-4
|autoscore=4
|n_web_uneval=10
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}