{{Rsnum
|rsid=1805012
|Gene=IL4R
|Chromosome=16
|position=27362643
|Orientation=plus
|GMAF=0.1019
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=IL4R
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 1.8 | 14.2 | 84.1
| HCB | 1.5 | 14.6 | 83.9
| JPT | 0.9 | 16.8 | 82.3
| YRI | 0.7 | 20.4 | 78.9
| ASW | 0.0 | 14.0 | 86.0
| CHB | 1.5 | 14.6 | 83.9
| CHD | 0.9 | 14.7 | 84.4
| GIH | 0.0 | 13.9 | 86.1
| LWK | 0.9 | 19.1 | 80.0
| MEX | 3.4 | 13.8 | 82.8
| MKK | 1.9 | 14.7 | 83.3
| TSI | 0.0 | 18.6 | 81.4
| HapMapRevision=28
}}{{PMID Auto
|PMID=19956098
|Title=Association analysis of SNPs in the IL4R locus with type I diabetes
|OA=1
}}

{{PMID Auto
|PMID=15660293
|Title=No evidence of association or interaction between the IL4RA, IL4, and IL13 genes in type 1 diabetes.
|OA=1
}}

{{PMID Auto
|PMID=15726497
|Title=Gene-environment interaction effects on the development of immune responses in the 1st year of life.
|OA=1
}}

{{PMID Auto
|PMID=19356949
|Title=Cytokine SNPs: Comparison of allele frequencies by race and implications for future studies.
|OA=1
}}

{{PMID Auto
|PMID=19759553
|Title=Genetic and environmental risk factors for childhood eczema development and allergic sensitization in the CCAAPS cohort.
|OA=1
}}

{{PMID Auto
|PMID=19956101
|Title=Overview of the Rapid Response data.
|OA=1
}}

{{PMID Auto
|PMID=19956106
|Title=Analysis of 19 genes for association with type I diabetes in the Type I Diabetes Genetics Consortium families.
|OA=1
}}

{{PMID Auto
|PMID=19956109
|Title=The Type I Diabetes Genetics Consortium 'Rapid Response' family-based candidate gene study: strategy, genes selection, and main outcome.
|OA=1
}}

{{PMID Auto
|PMID=20298583
|Title=Association of IL-4RA single nucleotide polymorphisms, HLA-DR and HLA-DQ in children with Alternaria-sensitive moderate-severe asthma.
|OA=1
}}

{{GET Evidence
|gene=IL4R
|aa_change=Cys431Arg
|aa_change_short=C431R
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs1805012
|overall_frequency_n=1061
|overall_frequency_d=10758
|overall_frequency=0.0986243
|n_genomes=9
|n_genomes_annotated=0
|n_haplomes=10
|n_articles=0
|n_articles_annotated=0
|pph2_score=0.999
|nblosum100=8
|autoscore=1
|webscore=N
}}

{{PMID Auto
|PMID=22902050
|Title=Using haplotype analysis to elucidate significant associations between genes and Hodgkin lymphoma.
|OA=1
}}

{{PMID Auto
|PMID=23663310
|Title=Investigating highly replicated asthma genes as candidate genes for allergic rhinitis.
|OA=1
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}