{{Rsnum
|rsid=1805017
|Gene=PLA2G7
|Chromosome=6
|position=46716485
|Orientation=minus
|GMAF=0.2525
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=PLA2G7
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 8.0 | 26.5 | 65.5
| HCB | 1.5 | 28.7 | 69.9
| JPT | 1.8 | 36.3 | 61.9
| YRI | 4.8 | 44.2 | 51.0
| ASW | 8.8 | 45.6 | 45.6
| CHB | 1.5 | 28.7 | 69.9
| CHD | 2.8 | 35.8 | 61.5
| GIH | 28.7 | 50.5 | 20.8
| LWK | 1.8 | 38.2 | 60.0
| MEX | 13.8 | 51.7 | 34.5
| MKK | 3.2 | 29.5 | 67.3
| TSI | 7.8 | 41.2 | 51.0
| HapMapRevision=28
}}

{{Venter SNP
|rsid=1805017
|allele=T
|frequency=0.22
|uid=1103652858688
|type=heterozygous_SNP
|hugo=PLA2G7
|ensembl gene=ENSG00000146070
|ensembl transcript=ENST00000274793
|sift=TOLERATED
|disease=Defects in PLA2G7 are the cause of platelet-activating factor acetylhydrolase deficiency (PLA2G7 deficiency) (MIM:601690). It is a trait which is present in 27% of Japanese. It could have a significant physiologic effect in the presence of inflammatory bodily responses.
}}

{{PMID Auto GWAS
|PMID=20442857
|Trait=Lipoprotein-associated phospholipase A2 activity and mass
|Title=Genome-wide association study of Lp-PLA(2) activity and mass in the Framingham Heart Study
|RiskAllele=T
|Pval=6E-14
|OR=11.10
|ORtxt=[NR] ng/mL increase
|OA=1
}}

{{PMID Auto GWAS
|PMID=22003152
|Trait=None
|Title=Eight genetic loci associated with variation in lipoprotein-associated phospholipase A2 mass and activity and coronary heart disease: meta-analysis of genome-wide association studies from five community-based studies.
|RiskAllele=T
|Pval=2E-23
|OR=0.0430
|ORtxt=None
|OA=1
}}

{{PMID Auto
|PMID=18204052
|Title=Comprehensive genetic analysis of the platelet activating factor acetylhydrolase (PLA2G7) gene and cardiovascular disease in case-control and family datasets.
|OA=1
}}

{{GET Evidence
|gene=PLA2G7
|aa_change=Arg92His
|aa_change_short=R92H
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs1805017
|overall_frequency_n=2871
|overall_frequency_d=10758
|overall_frequency=0.266871
|n_genomes=29
|n_genomes_annotated=0
|n_haplomes=33
|n_articles=0
|n_articles_annotated=0
|nblosum100=1
|autoscore=0
|webscore=N
}}

{{PMID Auto
|PMID=23404648
|Title=An association study between genetic polymorphisms related to lipoprotein-associated phospholipase A(2) and coronary heart disease
|OA=1
}}

{{ClinVar
|ALT=T
|CAF=0.7475; 0.2525
|CHROM=6
|CLNACC=RCV000049573.1
|CLNALLE=1
|CLNDBN=not provided
|CLNHGVS=NC_000006.11:g.46684222C>T
|CLNORIGIN=0
|CLNSIG=1
|COMMON=1
|Disease=not provided
|FwdALT=A
|FwdREF=G
|GENEINFO=PLA2G7:7941
|GENE_ID=7941
|GENE_NAME=PLA2G7
|REF=C
|RSPOS=46684222
|Reversed=1
|SAO=1
|SSR=0
|Tags=RV;PM;PMC;S3D;SLO;VLD;G5;HD;GNO;KGPhase1;KGPROD;OTHERKG;PH3;LSD;MTP;OM
|VC=SNV
|VP=0x050368000000150517130100
|WGT=0
|dbSNPBuildID=89
|rsid=1805017
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}