{{Rsnum
|rsid=1805034
|Gene=TNFRSF11A
|Chromosome=18
|position=62360008
|Orientation=plus
|GMAF=0.3953
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=TNFRSF11A
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 29.5 | 47.3 | 23.2
| HCB | 16.9 | 41.9 | 41.2
| JPT | 9.7 | 46.9 | 43.4
| YRI | 15.6 | 41.5 | 42.9
| ASW | 12.3 | 52.6 | 35.1
| CHB | 16.9 | 41.9 | 41.2
| CHD | 10.1 | 42.2 | 47.7
| GIH | 27.7 | 55.4 | 16.8
| LWK | 3.6 | 26.4 | 70.0
| MEX | 6.9 | 50.0 | 43.1
| MKK | 5.9 | 37.3 | 56.9
| TSI | 25.5 | 42.2 | 32.4
| HapMapRevision=28
}}{{PMID Auto
|PMID=20231205
|Title=Genetic Variations in Genes Encoding RANK, RANKL, and OPG in Rheumatoid Arthritis: A Case-Control Study
}}

{{PMID Auto
|PMID=20564239
|Title=Genetic variation in the TNFRSF11A gene encoding RANK is associated with susceptibility to Paget's disease of bone
}}

{{PMID Auto
|PMID=21760914
|Title=Pathway-based association analyses identified TRAIL pathway for osteoporotic fractures
|OA=1
}}

{{PMID|22023082|OA=1
}} Association analyses suggest the effects of RANK and RANKL on age at menarche in Chinese women.

{{GET Evidence
|gene=TNFRSF11A
|aa_change=Ala192Val
|aa_change_short=A192V
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs1805034
|overall_frequency_n=5912
|overall_frequency_d=10758
|overall_frequency=0.549545
|n_genomes=49
|n_genomes_annotated=0
|n_haplomes=76
|n_articles=0
|n_articles_annotated=0
|gene_in_genetests=Y
|genetests_testable=Y
|nblosum100=2
|autoscore=1
|webscore=N
}}

{{PMID Auto
|PMID=23369128
|Title=Genetic polymorphism of the OPG gene associated with breast cancer
|OA=1
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}