{{Rsnum
|rsid=1805128
|Gene=KCNE1
|Chromosome=21
|position=34449382
|Orientation=plus
|ReferenceAllele=G
|MissenseAllele=A
|GMAF=0.005051
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=KCNE1
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 0.0 | 4.6 | 95.4
| HCB | 0.0 | 0.0 | 100.0
| JPT | 0.0 | 2.3 | 97.7
| YRI | 0.0 | 0.0 | 100.0
| ASW | 0.0 | 0.0 | 0.0
| CHB | 0.0 | 0.0 | 100.0
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 0.0 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}
[http://blog.23andme.com/2009/03/23/snpwatch-researchers-identify-genetic-variants-linked-to-heart-rhythm-and-possibly-sudden-cardiac-death/ 23andMe blog] Influences [[QT interval]]

{{omim
|id=176261
|desc=POTASSIUM CHANNEL, VOLTAGE-GATED, ISK-RELATED SUBFAMILY, MEMBER 1;
|rsnum=1805128
}}

{{PharmGKB
|RSID=rs1805128
|Name_s=KCNE1:Asp85Asn
|Gene_s=KCNE1
|Feature=Exon/NonSyn
|Evidence=PubMed ID:16823764
|Annotation=Associated with noise-induced hearing loss.
|Drugs=
|Drug Classes=
|Diseases=
|Curation Level=Curated
|PharmGKB Accession ID=PA161145085
}}

{{omim
|id=176261
|rsnum=1805128
|variant=0005
}}

{{PMID Auto
|PMID=22100668
|Title=A Large Candidate Gene Survey Identifies the KCNE1 D85N Polymorphism as a Possible Modulator of Drug-Induced Torsades de Pointes
|OA=1
}}

{{ClinVar
|rsid=1805128
|Reversed=1
|FwdREF=G
|FwdALT=A
|REF=C
|ALT=T
|RSPOS=35821680
|CHROM=21
|GMAF=0.005
|dbSNPBuildID=89
|SSR=0
|SAO=1
|VP=0x050378000000040517110101
|GENEINFO=KCNE1:3753
|GENE_NAME=KCNE1
|GENE_ID=3753
|WGT=0
|VC=SNV
|CLNALLE=1
|CLNHGVS=NC_000021.8:g.35821680C>T
|CLNORIGIN=1
|CLNSIG=255
|Tags=RV;PM;TPA;PMC;S3D;SLO;VLD;HD;GNO;KGPhase1;KGPROD;OTHERKG;PH3;LSD;OM
|CAF=0.9949; 0.005051
|CLNACC=RCV000014422.1; RCV000014423.24; RCV000035353.1; RCV000057858.1
|CLNDBN=Long QT syndrome 5, acquired, susceptibility to; Long QT syndrome 2/5; AllHighlyPenetrant; not provided
|CLNDSDB=MedGen
|CLNDSDBID=C3150957; CN169374
|CLNSRC=OMIM Allelic Variant
|CLNSRCID=176261.0005
|COMMON=1
|Disease=Long QT syndrome 5; Long QT syndrome 2/5; AllHighlyPenetrant; not provided
}}

{{PMID Auto
|PMID=19019189
|Title=Common candidate gene variants are associated with QT interval duration in the general population.
|OA=1
}}

{{PMID Auto
|PMID=19305408
|Title=Common variants at ten loci influence QT interval duration in the QTGEN Study.
|OA=1
}}

{{PMID Auto
|PMID=19530973
|Title=Genetic variation in the rhythmonome: ethnic variation and haplotype structure in candidate genes for arrhythmias.
|OA=1
}}

{{PMID Auto
|PMID=19587794
|Title=Common genetic variation near the phospholamban gene is associated with cardiac repolarisation: meta-analysis of three genome-wide association studies.
|OA=1
}}

{{PMID Auto
|PMID=150516
|Title=VE, threat of controls slow spending.
}}

{{PMID Auto
|PMID=9445165
|Title=Mutation of the gene for IsK associated with both Jervell and Lange-Nielsen and Romano-Ward forms of Long-QT syndrome.
}}

{{PMID Auto
|PMID=10807545
|Title=Twenty single nucleotide polymorphisms (SNPs) and their allelic frequencies in four genes that are responsible for familial long QT syndrome in the Japanese population.
}}

{{PMID Auto
|PMID=12402336
|Title=DHPLC analysis of potassium ion channel genes in congenital long QT syndrome.
}}

{{PMID Auto
|PMID=14661677
|Title=Ethnic differences in cardiac potassium channel variants: implications for genetic susceptibility to sudden cardiac death and genetic testing for congenital long QT syndrome.
}}

{{PMID Auto
|PMID=14760488
|Title=Genetic variations of KCNQ1, KCNH2, SCN5A, KCNE1, and KCNE2 in drug-induced long QT syndrome patients.
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}