{{Rsnum
|rsid=1830084
|Gene=SRPRB
|Chromosome=3
|position=133789620
|Orientation=minus
|GMAF=0.3365
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;T)
|geno3=(T;T)
|Gene_s=SRPRB
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;T)
| geno3=(T;T)
| CEU | 11.5 | 47.8 | 40.7
| HCB | 18.2 | 46.7 | 35.0
| JPT | 28.3 | 43.4 | 28.3
| YRI | 1.4 | 15.6 | 83.0
| ASW | 5.3 | 31.6 | 63.2
| CHB | 18.2 | 46.7 | 35.0
| CHD | 27.5 | 46.8 | 25.7
| GIH | 18.8 | 55.4 | 25.7
| LWK | 1.8 | 26.4 | 71.8
| MEX | 12.1 | 51.7 | 36.2
| MKK | 0.0 | 26.3 | 73.7
| TSI | 11.8 | 47.1 | 41.2
| HapMapRevision=28
}}
{{PMID Auto GWAS
|PMID=19084217
|Trait=Serum markers of iron status
|Title=Variants in TF and HFE explain approximately 40% of genetic variation in serum-transferrin levels
|RiskAllele=A
|Pval=1E-9
|OR=0.43
|ORtxt=[NR] SD increase
|OA=1
}}

{{omim
|desc=TRANSFERRIN; TF
|id=190000
|rsnum=1830084
}}

{{PharmGKB
|RSID=rs1830084
|Name_s=
|Gene_s=-
|Feature=
|Evidence=PubMed ID:19084217
|Annotation=In a GWAS performed on 411 adolescent twins and their siblings, all of Australians of European descent, this SNP was found to be significantly associated with serum transferrin (p total association test = 1.0 x 10(-9);p within-family test= 2.2 x 10 x (-5)).
|Drugs=
|Drug Classes=
|Diseases=
|Curation Level=Curated
|PharmGKB Accession ID=PA164920506
}}

{{PharmGKB
|RSID=rs1830084
|Name_s=
|Gene_s=-
|Feature=
|Evidence=PubMed ID:19084217; Web Resource:http://www.genome.gov/gwastudies/
|Annotation=GWAS results: Variants in TF and HFE explain approximately 40% of genetic variation in serum-transferrin levels. (Initial Sample Size: 411 family members; Replication Sample Size: NR); (Region: 3q22.1; Reported Gene(s): TF; Risk Allele: rs1830084-A); (p-value= 0.000000001).This variant is associated with Serum markers of iron status.
|Drugs=
|Drug Classes=
|Diseases=
|Curation Level=Non-Curated
|PharmGKB Accession ID=PA164740102
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs1830084
|overall_frequency_n=37
|overall_frequency_d=128
|overall_frequency=0.289062
|n_genomes=24
|n_genomes_annotated=0
|n_haplomes=29
|n_articles=1
|n_articles_annotated=0
|in_gwas=Y
|in_pharmgkb=Y
|autoscore=2
|webscore=N
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}