{{Rsnum
|rsid=1861973
|Gene=EN2
|Chromosome=7
|position=155461450
|Orientation=plus
|GMAF=0.2181
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=EN2
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 54.0 | 41.6 | 4.4
| HCB | 81.0 | 19.0 | 0.0
| JPT | 94.6 | 5.4 | 0.0
| YRI | 60.3 | 34.2 | 5.5
| ASW | 40.4 | 50.9 | 8.8
| CHB | 81.0 | 19.0 | 0.0
| CHD | 85.3 | 14.7 | 0.0
| GIH | 45.5 | 46.5 | 7.9
| LWK | 57.3 | 32.7 | 10.0
| MEX | 57.9 | 36.8 | 5.3
| MKK | 36.7 | 53.3 | 10.0
| TSI | 49.0 | 44.1 | 6.9
| HapMapRevision=28
}}

[http://precedings.nature.com/documents/2366/version/1 nature] The inheritance of the AC haplotype of [[rs1861972]] – [[rs1861973]], the C allele of [[rs1811399]], and the C allele of [[rs1234747]] may contribute to [[autism]] by affecting [[microRNA]]

{{PMID|18424904}} [[rs1861972]](A) + [[rs1861973]](C) haplotype assoc. with '''protective''' effect against autism in a study of 818 Han Chinese (184 diag. autistics, 225 unrelated volunteers, 409 randomly selected)

{{ neighbor
| rsid = 1861972
| distance = 152
}}

{{omim
|desc=AUTISM, SUSCEPTIBILITY TO, 10; AUTS10
|id=611016
|rsnum=1861973
}}

{{omim
|id=131310
|desc=ENGRAILED 2; EN2
|rsnum=1861973
}}

{{PMID Auto
|PMID=20523082
|Title=Intronic single nucleotide polymorphisms of engrailed homeobox 2 modulate the disease vulnerability of autism in a han chinese population
}}

{{omim
|id=131310
|rsnum=1861973
|variant=0001
}}

{{PMID Auto
|PMID=15024396
|Title=Association of the homeobox transcription factor, ENGRAILED 2, 3, with autism spectrum disorder.
}}

{{PMID Auto
|PMID=16252243
|Title=Support for the homeobox transcription factor gene ENGRAILED 2 as an autism spectrum disorder susceptibility locus.
|OA=1
}}

{{PMID Auto
|PMID=17948901
|Title=Association of the ENGRAILED 2 (EN2) gene with autism in Chinese Han population.
}}

{{PMID Auto
|PMID=19615670
|Title=Autism-associated haplotype affects the regulation of the homeobox gene, ENGRAILED 2.
|OA=1
}}

{{PMID Auto
|PMID=20050924
|Title=Family-based studies indicate association of Engrailed 2 gene with autism in an Indian population.
}}

{{PMID Auto
|PMID=22180456
|Title=Cut-like homeobox 1 and nuclear factor I/B mediate ENGRAILED2 autism spectrum disorder-associated haplotype function.
|OA=1
}}

{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}