{{Rsnum
|rsid=1884444
|Gene=IL23R
|Chromosome=1
|position=67168129
|Orientation=plus
|ReferenceAllele=G
|MissenseAllele=T
|GMAF=0.4816
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(G;G)
|geno2=(G;T)
|geno3=(T;T)
|Gene_s=IL23R
}}{{ population diversity
| geno1=(G;G)
| geno2=(G;T)
| geno3=(T;T)
| CEU | 22.3 | 52.7 | 25.0
| HCB | 13.9 | 46.7 | 39.4
| JPT | 15.9 | 43.4 | 40.7
| YRI | 21.9 | 51.4 | 26.7
| ASW | 21.1 | 66.7 | 12.3
| CHB | 13.9 | 46.7 | 39.4
| CHD | 11.0 | 43.1 | 45.9
| GIH | 14.9 | 46.5 | 38.6
| LWK | 40.9 | 43.6 | 15.5
| MEX | 39.7 | 48.3 | 12.1
| MKK | 53.8 | 37.8 | 8.3
| TSI | 19.6 | 50.0 | 30.4
| HapMapRevision=28
}}
{{PMID Auto
|PMID=19317742
|Title=Interleukin-23 receptor gene polymorphisms is associated with dilated cardiomyopathy in Chinese Han population.
}}

{{PMID Auto
|PMID=19895338
|Title=The Association Between Interleukin-23 Receptor Gene Polymorphisms and Systemic Lupus Erythematosus
}}

{{PMID Auto
|PMID=20607725
|Title=A nonsynonymous polymorphism in IL23R gene is associated with risk of gastric cancer in a Chinese population
}}

{{PMID Auto
|PMID=22483685
|Title=Interactions between IL17A, IL23R, and STAT4 polymorphisms confer susceptibility to intestinal Behcet's disease in Korean population
}}

{{PMID Auto
|PMID=22735941
|Title=IL-23R polymorphisms, HBV infection, and risk of hepatocellular carcinoma in a high-risk Chinese population
}}

{{PMID Auto
|PMID=17236132
|Title=A large-scale genetic association study confirms IL12B and leads to the identification of IL23R as psoriasis-risk genes.
|OA=1
}}

{{PMID Auto
|PMID=17606463
|Title=Functional variants of interleukin-23 receptor gene confer risk for rheumatoid arthritis but not for systemic sclerosis.
}}

{{PMID Auto
|PMID=18470928
|Title=IL23R haplotypes provide a large population attributable risk for Crohn's disease.
|OA=1
}}

{{PMID Auto
|PMID=18715515
|Title=Lack of evidence for association of primary sclerosing cholangitis and primary biliary cirrhosis with risk alleles for Crohn's disease in Polish patients.
|OA=1
}}

{{PMID Auto
|PMID=19103559
|Title=[Susceptibility genetic variants in Hungarian morbus Crohn and ulcerative colitis patients].
}}

{{PMID Auto
|PMID=19918037
|Title=Association of interleukin 23 receptor polymorphisms with anti-topoisomerase-I positivity and pulmonary hypertension in systemic sclerosis.
|OA=1
}}

{{PMID Auto
|PMID=21304977
|Title=An investigation of genome-wide studies reported susceptibility loci for ulcerative colitis shows limited replication in north Indians.
|OA=1
}}

{{PMID Auto
|PMID=21484795
|Title=Potentially functional polymorphisms in IL-23 receptor and risk of esophageal cancer in a Chinese population.
}}

{{GET Evidence
|gene=IL23R
|aa_change=Gln3His
|aa_change_short=Q3H
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs1884444
|overall_frequency_n=5598
|overall_frequency_d=10758
|overall_frequency=0.520357
|n_genomes=38
|n_genomes_annotated=0
|n_haplomes=54
|n_articles=0
|n_articles_annotated=0
|pph2_score=0.001
|nblosum100=-1
|autoscore=0
|webscore=N
}}

{{PMID Auto
|PMID=23093364
|Title=Difference of interleukin-23 receptor gene haplotype variants in ulcerative colitis compared to Crohn's disease and psoriasis
}}

{{PMID Auto
|PMID=23239971
|Title=A miRNA Binding Site Single-Nucleotide Polymorphism in the 3'-UTR Region of the IL23R Gene Is Associated with Breast Cancer
|OA=1
}}

{{PMID Auto
|PMID=23393581
|Title=Potentially Functional Polymorphism in IL-23 Receptor and Risk of Acute Myeloid Leukemia in a Chinese Population
|OA=1
}}

{{PMID Auto
|PMID=23807368
|Title=Correlation between interleukin‑23 receptor gene polymorphisms and risk of hepatitis B virus infection in patients
}}

{{PMID Auto
|PMID=24076440
|Title=Interleukin-23 receptor genetic variants contribute to susceptibility of multiple cancers
}}

{{PMID Auto
|PMID=23754344
|Title=Lack of association between IL-23R gene polymorphisms and systemic lupus erythematosus in a Chinese population
}}

{{PMID Auto
|PMID=23564312
|Title=Polymorphisms of the IL-23R gene are associated with primary immune thrombocytopenia but not with the clinical outcome of pulsed high-dose dexamethasone therapy.
}}

{{PMID Auto
|PMID=24912586
|Title=A non-synonymous polymorphism in IL-23R Gene (rs1884444) is associated with reduced risk to schistosomiasis-associated Immune Reconstitution Inflammatory Syndrome in a Kenyan population
}}

{{PMID Auto
|PMID=25192515
|Title=Functional Polymorphisms in Interleukin-23 Receptor and Susceptibility to Coronary Artery Disease
}}
{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}