{{Rsnum
|rsid=1885120
|Gene=MYH7B
|Chromosome=20
|position=34989186
|Orientation=plus
|GMAF=0.01974
|Gene_s=MIR499A,MYH7B
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;G)
|geno3=(G;G)
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;G)
| geno3=(G;G)
| CEU | 0.9 | 12.4 | 86.7
| HCB | 0.0 | 0.0 | 100.0
| JPT | 0.0 | 0.0 | 100.0
| YRI | 0.0 | 0.0 | 100.0
| ASW | 0.0 | 0.0 | 0.0
| CHB | 0.0 | 0.0 | 100.0
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 2.0 | 98.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 1.7 | 98.3
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 5.9 | 94.1
| HapMapRevision=28
}}

{{PMID|18488026|OA=1
}} 2,019 cases and 2,105 controls. Using pooling, we identified a new melanoma risk locus on chromosome 20 ([[rs910873]] and [[rs1885120]] combined P less than 1 10-15. The per allele odds ratio was 1.75 (1.53, 2.01), with evidence for stronger association in early-onset cases.

{{omim
|desc=MELANOMA, CUTANEOUS MALIGNANT, SUSCEPTIBILITY TO, 7; CMM7
|id=612263
|rsnum=1885120
}}

{{PharmGKB
|RSID=rs1885120
|Name_s=
|Gene_s=MYH7B
|Feature=
|Evidence=PubMed ID:18488026
|Annotation=SNP on chromosome 20 is highly associated with melanoma risk. rs1885120 (and, through LD, rs910873) seems to be related to early onset.
|Drugs=
|Drug Classes=
|Diseases=Melanoma
|Curation Level=Curated
|PharmGKB Accession ID=PA161925570
}}

{{PMID Auto
|PMID=21221757
|Title=ASIP genetic variants and the number of non-melanoma skin cancers
|OA=1
}}

{{PMID Auto
|PMID=19578364
|Title=Genome-wide association study identifies three loci associated with melanoma risk.
|OA=1
}}

{{PMID Auto
|PMID=19995372
|Title=Melanoma susceptibility variants on chromosome 20q11.22 are associated with pigmentary traits and the risk of nonmelanoma skin cancer.
|OA=1
}}

{{PMID Auto
|PMID=20224305
|Title=Modest association of malignant melanoma with the rs910873 and rs1885120 markers on chromosome 20: a population-based study.
}}

{{GET Evidence
|impact=pharmacogenetic
|qualified_impact=Insufficiently evaluated pharmacogenetic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs1885120
|overall_frequency_n=126
|overall_frequency_d=128
|overall_frequency=0.984375
|n_genomes=55
|n_genomes_annotated=0
|n_haplomes=106
|n_articles=2
|n_articles_annotated=2
|in_pharmgkb=Y
|autoscore=1
|webscore=N
|summary_short=may be associated with cutaneous melanoma
}}

{{PMID Auto
|PMID=23393597
|Title=Replication and Predictive Value of SNPs Associated with Melanoma and Pigmentation Traits in a Southern European Case-Control Study
|OA=1
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | HumanOmni1Quad}}