{{Rsnum
|rsid=1937
|Gene=TFAM
|Chromosome=10
|position=60145342
|Orientation=plus
|GMAF=0.09412
|Assembly=GRCh37
|GenomeBuild=37.1
|dbSNPBuild=132
|geno1=(C;C)
|geno2=(C;G)
|geno3=(G;G)
}}
{{ population diversity
| geno1=(C;C)
| geno2=(C;G)
| geno3=(G;G)
| CEU | 1.5 | 20.0 | 78.5
| HCB | 2.2 | 31.1 | 66.7
| JPT | 2.3 | 20.5 | 77.3
| YRI | 0.0 | 0.0 | 100.0
| ASW | 0.0 | 0.0 | 0.0
| CHB | 2.2 | 31.1 | 66.7
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 0.0 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}{{PMID Auto
|PMID=20977898
|Title=Mitochondrial transcription factor A (TFAM) polymorphisms and risk of late-onset Alzheimer's disease in Han Chinese
}}

The C allele of [[rs1937]] appears to be protective against late-onset [[Alzheimer's disease]] in Han Chinese. {{PMID|20977898}}

{{PMID Auto
|PMID=15464268
|Title=Possible association of mitochondrial transcription factor A (TFAM) genotype with sporadic Alzheimer disease.
}}

{{PMID Auto
|PMID=16385451
|Title=A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.
|OA=1
}}

{{PMID Auto
|PMID=17497594
|Title=Relationship between TFAM gene polymorphisms and endurance capacity in response to training.
}}

{{PMID Auto
|PMID=17537576
|Title=Association study of two genetic variants in mitochondrial transcription factor A (TFAM) in Alzheimer's and Parkinson's disease.
}}

{{PMID Auto
|PMID=18430995
|Title=Mitochondrial transcription factor A (TFAM) gene variation and risk of late-onset Alzheimer's disease.
}}

{{PMID Auto
|PMID=18451773
|Title=A decreased mitochondrial DNA content is related to insulin resistance in adolescents.
}}

{{GET Evidence
|gene=TFAM
|aa_change=Ser12Thr
|aa_change_short=S12T
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs1937
|overall_frequency_n=763
|overall_frequency_d=10752
|overall_frequency=0.0709635
|n_genomes=6
|n_genomes_annotated=0
|n_haplomes=8
|n_articles=0
|n_articles_annotated=0
|pph2_score=0.028
|nblosum100=-2
|autoscore=0
|webscore=N
}}

{{PMID Auto
|PMID=23186209
|Title=Mitochondriogenesis genes and extreme longevity.
}}

{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}