{{Rsnum
|rsid=193922816
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Chromosome=19
|Orientation=plus
|Gene=RYR1
|position=38500642
|Gene_s=RYR1
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
}}[[rs193922816]], aka p.Arg2454Cys or p.R2454C, is a SNP in the [[RYR1]] gene considered causative for [[malignant hyperthermia]].