{{Rsnum
|rsid=199474720
|Chromosome=1
|Orientation=minus
|geno1=(A;A)
|geno2=(A;C)
|geno3=(C;C)
|Gene=TPM3
|position=154167938
|Gene_s=TPM3
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
}}{{ClinVar
|rsid=199474720
|Reversed=1
|FwdREF=A
|FwdALT=C
|REF=T
|ALT=G
|RSPOS=154167938
|CHROM=1
|dbSNPBuildID=136
|SSR=0
|SAO=1
|VP=0x050168080205000002110100
|WGT=1
|VC=SNV
|CLNALLE=1
|CLNHGVS=NC_000001.11:g.154167938T>G
|CLNSRC=ClinVar; GeneReviews; OMIM Allelic Variant
|CLNORIGIN=1
|CLNSRCID=NM_001043353.1:c.664+2462A>C; NM_152263.3:c.857A>C; NBK1259; 191030.0002
|CLNSIG=5
|CLNCUI=C1836448; C1836448
|CLNDBN=Nemaline myopathy 1
|Disease=Nemaline myopathy 1
|CLNACC=RCV000013260.23
|Tags=RV;PM;PMC;SLO;REF;INT;ASP;OTHERKG;LSD;OM
|CLNDSDB=GeneReviews:GeneReviews:MedGen:OMIM:Orphanet:Orphanet
|CLNDSDBID=NBK1259:NBK1288:C1836448:609284:ORPHA171881:ORPHA607
|GENEINFO=TPM3:7170
|GENE_ID=7170
|GENE_NAME=TPM3
}}{{PMID|12196661}} Mutations of the slow muscle alpha-tropomyosin gene, TPM3, are a rare cause of nemaline myopathy.

{{PMID|19953533|OA=1
}} Mutations of tropomyosin 3 (TPM3) are common and associated with type 1 myofiber hypotrophy in congenital fiber type disproportion.