{{Rsnum
|rsid=2000813
|Gene=LIPG
|Chromosome=18
|position=49567494
|Orientation=plus
|ReferenceAllele=C
|MissenseAllele=T
|GMAF=0.2438
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=LIPG
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 50.5 | 43.2 | 6.3
| HCB | 46.6 | 42.1 | 11.3
| JPT | 55.9 | 35.1 | 9.0
| YRI | 95.9 | 4.1 | 0.0
| ASW | 82.1 | 14.3 | 3.6
| CHB | 46.6 | 42.1 | 11.3
| CHD | 40.2 | 46.7 | 13.1
| GIH | 46.4 | 38.1 | 15.5
| LWK | 86.2 | 13.8 | 0.0
| MEX | 50.0 | 46.6 | 3.4
| MKK | 65.4 | 30.1 | 4.6
| TSI | 44.6 | 43.6 | 11.9
| HapMapRevision=28
}}{{PMID Auto
|PMID=19380136
|Title=Physical inactivity interacts with an endothelial lipase polymorphism to modulate high density lipoprotein cholesterol in the GOLDN study
|OA=1
}}

{{PMID Auto
|PMID=20466371
|Title=Lack of association between common genetic variation in endothelial lipase (LIPG) and the risk for CAD and DVT
}}
{{PMID Auto
|PMID=20923576
|Title=Association of the LIPG 584C&gt;T polymorphism and serum lipid levels in the Guangxi Bai Ku Yao and Han populations
|OA=1
}}

{{PMID Auto
|PMID=22174694
|Title=Mining the LIPG Allelic Spectrum Reveals the Contribution of Rare and Common Regulatory Variants to HDL Cholesterol
|OA=1
}}

{{PMID Auto
|PMID=18078817
|Title=Multiple genetic determinants of plasma lipid levels in Caribbean Hispanics.
|OA=1
}}

{{PMID Auto
|PMID=19041386
|Title=Genetic-epidemiological evidence on genes associated with HDL cholesterol levels: a systematic in-depth review.
|OA=1
}}

{{PMID Auto
|PMID=19287092
|Title=Loss-of-function variants in endothelial lipase are a cause of elevated HDL cholesterol in humans.
|OA=1
}}

{{PMID Auto
|PMID=21145773
|Title=Association of endothelial lipase Thr111Ile polymorphism with lipid metabolism and microvascular complications in type 2 diabetic patients.
}}

{{PMID Auto
|PMID=21816559
|Title=Interactions of the LIPG 584C>T polymorphism and alcohol consumption on serum lipid levels.
}}

{{GET Evidence
|gene=LIPG
|aa_change=Thr111Ile
|aa_change_short=T111I
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs2000813
|overall_frequency_n=2459
|overall_frequency_d=10758
|overall_frequency=0.228574
|n_genomes=15
|n_genomes_annotated=0
|n_haplomes=18
|n_articles=0
|n_articles_annotated=0
|nblosum100=3
|autoscore=0
|webscore=N
}}

{{PMID Auto
|PMID=23355348
|Title=Interactions of several single nucleotide polymorphisms and high body mass index on serum lipid traits.
}}

{{PMID Auto
|PMID=24852509
|Title=Association of endothelial lipase Thr111Ile polymorphism with proliferative retinopathy in type 2 diabetes patients
}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}