{{Rsnum
|rsid=2014307
|Gene=ARMS2
|Chromosome=10
|position=124217632
|Orientation=minus
|GMAF=0.3641
|Assembly=GRCh37
|GenomeBuild=37.1
|dbSNPBuild=131
|geno1=(A;A)
|geno2=(A;C)
|geno3=(C;C)
}}
{{ population diversity
| geno1=(A;A)
| geno2=(A;C)
| geno3=(C;C)
| CEU | 14.3 | 42.0 | 43.8
| HCB | 6.8 | 54.1 | 39.1
| JPT | 8.0 | 44.2 | 47.8
| YRI | 12.3 | 40.4 | 47.3
| ASW | 7.1 | 32.1 | 60.7
| CHB | 6.8 | 54.1 | 39.1
| CHD | 11.3 | 45.3 | 43.4
| GIH | 14.9 | 52.5 | 32.7
| LWK | 7.3 | 40.0 | 52.7
| MEX | 20.7 | 51.7 | 27.6
| MKK | 2.6 | 32.9 | 64.5
| TSI | 21.6 | 42.2 | 36.3
| HapMapRevision=28
}}[http://7thspace.com/headlines/283954/the_neincbi_dbgap_database_genotypes_and_haplotypes_that_may_predispose_to_risk_of_neovascular_age_related_macular_degeneration.html news] 

[[rs572515]] was the most significantly associated with AMD risk (P <10-6).

[[rs9288410]] and [[rs2014307]] (PLEKHA1/HTRA1) on 10q26 were significantly associated with AMD status (P= .03 and P <10-6 respectively). After controlling for smoking history, gender and age, the most significant gene-gene interaction appears to be between [[rs10801575]] (CFH) and [[rs2014307]] (PLEKHA1/HTRA1) (P <10-11).

{{PMID Auto
|PMID=18541031
|Title=The NEI/NCBI dbGAP database: genotypes and haplotypes that may specifically predispose to risk of neovascular age-related macular degeneration.
|OA=1
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}