{{Rsnum
|rsid=2020908
|Gene=MSH6
|Chromosome=2
|position=47799169
|Orientation=plus
|ReferenceAllele=C
|MissenseAllele=G
|GMAF=0.004132
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;G)
|geno3=(G;G)
|Gene_s=MSH6
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;G)
| geno3=(G;G)
| CEU | 98.5 | 1.5 | 0.0
| HCB | 100.0 | 0.0 | 0.0
| JPT | 97.7 | 2.3 | 0.0
| YRI | 100.0 | 0.0 | 0.0
| ASW | 0.0 | 0.0 | 0.0
| CHB | 100.0 | 0.0 | 0.0
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 0.0 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}{{Venter SNP
|rsid=2020908
|allele=G
|frequency=0.008
|uid=1103658091309
|type=heterozygous_SNP
|hugo=MSH6
|ensembl gene=ENSG00000116062
|ensembl transcript=ENST00000234420
|sift=AFFECT FUNCTION
|disease=Defects in MSH6 are a cause of susceptibility to endometrial cancer (MIM:608089).
}}

{{ClinVar
|rsid=2020908
|Reversed=0
|FwdREF=C
|FwdALT=G
|REF=C
|ALT=G
|RSPOS=48026308
|CHROM=2
|GMAF=0.0041
|dbSNPBuildID=98
|SSR=0
|SAO=1
|VP=0x050368000000040517100100
|GENEINFO=MSH6:2956
|GENE_NAME=MSH6
|GENE_ID=2956
|WGT=0
|VC=SNV
|CLNALLE=1
|CLNHGVS=NC_000002.11:g.48026308C>G
|CLNSRC=InSiGHT
|CLNORIGIN=1
|CLNSIG=2
|CLNDBN=Lynch syndrome; not provided
|Disease=Lynch syndrome; not provided
|Tags=PM;PMC;S3D;SLO;VLD;HD;GNO;KGPhase1;KGPROD;OTHERKG;PH3;LSD
|CAF=0.9959; 0.004132
|CLNACC=RCV000030259.2; RCV000034490.1
|CLNDSDB=GeneReviews:MedGen:SNOMED_CT
|CLNDSDBID=NBK1211:C0009405:315058005
|COMMON=1
|CLNSRCID=c.1186C>G
}}

{{PMID Auto
|PMID=19389263
|Title=Investigation on the role of nsSNPs in HNPCC genes--a bioinformatics approach.
|OA=1
}}

{{PMID Auto
|PMID=20805886
|Title=Unique DNA repair gene variations and potential associations with the primary antibody deficiency syndromes IgAD and CVID.
|OA=1
}}

{{PMID Auto
|PMID=10508
|Title=A new form of antihistamine--the H2-receptor antagonist.
}}

{{PMID Auto
|PMID=10537275
|Title=Germ-line msh6 mutations in colorectal cancer families.
}}

{{PMID Auto
|PMID=15340264
|Title=Genotyping possible polymorphic variants of human mismatch repair genes in healthy Korean individuals and sporadic colorectal cancer patients.
}}

{{PMID Auto
|PMID=17417778
|Title=Genetic investigation of DNA-repair pathway genes PMS2, MLH1, MSH2, MSH6, MUTYH, OGG1 and MTH1 in sporadic colon cancer.
}}

{{PMID Auto
|PMID=18566915
|Title=Major contribution from recurrent alterations and MSH6 mutations in the Danish Lynch syndrome population.
}}

{{PMID Auto
|PMID=19250818
|Title=A new strategy to screen MMR genes in Lynch Syndrome: HA-CAE, MLPA and RT-PCR.
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}