{{Rsnum
|rsid=2020912
|Gene=MSH6
|Chromosome=2
|position=47800616
|Orientation=plus
|GMAF=0.005051
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=MSH6
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 0.0 | 1.8 | 98.2
| HCB | 0.0 | 1.5 | 98.5
| JPT | 0.0 | 0.9 | 99.1
| YRI | 0.0 | 2.1 | 97.9
| ASW | 0.0 | 3.6 | 96.4
| CHB | 0.0 | 1.5 | 98.5
| CHD | 0.0 | 0.9 | 99.1
| GIH | 0.0 | 2.0 | 98.0
| LWK | 0.0 | 0.9 | 99.1
| MEX | 0.0 | 0.0 | 0.0
| MKK | 0.0 | 0.6 | 99.4
| TSI | 0.0 | 5.9 | 94.1
| HapMapRevision=28
}}{{omim
|id=600678
|rsnum=2020912
|variant=0006
}}

{{ClinVar
|rsid=2020912
|Reversed=0
|FwdREF=T
|FwdALT=C
|REF=T
|ALT=C
|RSPOS=48027755
|CHROM=2
|GMAF=0.005
|dbSNPBuildID=98
|SSR=0
|SAO=1
|VP=0x050368000000050517110100
|GENEINFO=MSH6:2956
|GENE_NAME=MSH6
|GENE_ID=2956
|WGT=0
|VC=SNV
|CLNALLE=1
|CLNHGVS=NC_000002.11:g.48027755T>C
|CLNORIGIN=1
|CLNSIG=5
|Tags=PM;PMC;S3D;SLO;VLD;G5;HD;GNO;KGPhase1;KGPROD;OTHERKG;PH3;LSD;OM
|CAF=0.9949; 0.005051
|CLNACC=RCV000009486.1; RCV000030264.2; RCV000034495.1
|CLNDBN=Colon cancer, hereditary nonpolyposis, type 5; Lynch syndrome; not provided
|CLNDSDB=GeneReviews:MedGen:SNOMED_CT
|CLNDSDBID=NBK1211:C0009405:315058005
|CLNSRC=InSiGHT; OMIM Allelic Variant
|CLNSRCID=c.2633T>C; 600678.0006
|COMMON=1
|Disease=Colon cancer; Lynch syndrome; not provided
}}

{{PMID Auto
|PMID=19389263
|Title=Investigation on the role of nsSNPs in HNPCC genes--a bioinformatics approach.
|OA=1
}}

{{PMID Auto
|PMID=18033
|Title=[Functional digestive troubles in old age (author's transl)].
}}

{{PMID Auto
|PMID=11709755
|Title=Molecular and clinical characteristics of MSH6 variants: an analysis of 25 index carriers of a germline variant.
|OA=1
}}

{{PMID Auto
|PMID=16885385
|Title=Screening for Lynch syndrome (hereditary nonpolyposis colorectal cancer) among endometrial cancer patients.
}}

{{PMID Auto
|PMID=16940983
|Title=MSH6 germline mutations in early-onset colorectal cancer patients without family history of the disease.
|OA=1
}}

{{PMID Auto
|PMID=18415027
|Title=Genome-wide copy neutral LOH is infrequent in familial and sporadic microsatellite unstable carcinomas.
}}

{{PMID Auto
|PMID=18790734
|Title=Hereditary cancer-associated missense mutations in hMSH6 uncouple ATP hydrolysis from DNA mismatch binding.
|OA=1
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}