{{Rsnum
|rsid=2066462
|Gene=MTHFR
|Chromosome=1
|position=11794839
|Orientation=plus
|GMAF=0.08815
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=MTHFR
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 77.4 | 22.6 | 0.0
| HCB | 80.5 | 17.1 | 2.4
| JPT | 71.9 | 28.1 | 0.0
| YRI | 80.7 | 19.3 | 0.0
| ASW | 0.0 | 0.0 | 0.0
| CHB | 80.5 | 17.1 | 2.4
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 0.0 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}{{PMID Auto
|PMID=20863444
|Title=Associations between the genetic polymorphisms of MTHFR and outcomes of methotrexate treatment in rheumatoid arthritis
}}

{{PMID Auto
|PMID=22241680
|Title=Deep sequencing study of the MTHFR gene to identify variants associated with myelomeningocele
|OA=1
}}

{{PMID|18538037|OA=1
}} A simple and accurate SNP scoring strategy based on typeIIS restriction endonuclease cleavage and matrix-assisted laser desorption/ionization mass spectrometry.

{{PMID Auto
|PMID=23270270
|Title=[Analysis of the MTHFR gene linkage disequilibrium structure and association of polymorphic gene variants with coronary atherosclerosis]
}}

{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}