{{Rsnum
|rsid=2069832
|Gene=IL6
|Chromosome=7
|position=22727814
|Orientation=plus
|GMAF=0.1837
|Gene_s=IL6,MIR632
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 31.9 | 43.4 | 24.8
| HCB | 0.0 | 0.0 | 0.0
| JPT | 0.0 | 0.0 | 0.0
| YRI | 0.0 | 0.0 | 0.0
| ASW | 0.0 | 19.3 | 80.7
| CHB | 0.0 | 0.0 | 0.0
| CHD | 0.0 | 0.9 | 99.1
| GIH | 1.0 | 21.8 | 77.2
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 34.5 | 65.5
| MKK | 0.0 | 9.6 | 90.4
| TSI | 14.7 | 42.2 | 43.1
| HapMapRevision=28
}}

{{PMID|18727828|OA=1
}}  [http://7thspace.com/headlines/291555/ischemic_stroke_risk_smoking_and_the_genetics_of_inflammation_in_a_biracial_population_the_stroke_prevention_in_young_women_study.html 7thspace] [[stroke]] [[rs2069832]](C) (African-American frequency = 92%) significantly associated with stroke only among African-Americans (age-adjusted: OR =2.2, 95% CI=1.0-5.0, p=0.049; risk factor adjusted: OR =2.5, 95% CI=1.0-6.5, p=0.05). 

{{ neighbor
| rsid = 2069830
| distance = 296
}}
{{ neighbor
| rsid = 2066992
| distance = 816
}}

{{PMID Auto
|PMID=22459738
|Title=Genetic and Immunological Evidence Implicates Interleukin 6 as a Susceptibility Gene for Leprosy Type 2 Reaction
}}

{{PMID|17594514|OA=1
}} Active and passive smoking, IL6, ESR1, and breast cancer risk.

{{PMID|17694420|OA=1
}} IL6 genotypes and colon and rectal cancer.

{{PMID|18239642|OA=1
}} Modifying effects of IL-6 polymorphisms on body size-associated breast cancer risk.

{{PMID|18420533|OA=1
}} The effect of IL6-174C/G polymorphism on postprandial triglyceride metabolism in the GOLDN studyboxs.

{{PMID|18496509|OA=1
}} An IL-6 haplotype on human chromosome 7p21 confers risk for impaired renal function in type 2 diabetic patients.

{{PMID|19035456|OA=1
}} Adipokine genes and prostate cancer risk.

{{PMID|19267250|OA=1
}} C-reactive protein, interleukin-6, and prostate cancer risk in men aged 65 years and older.

{{PMID|19359268|OA=1
}} Associations of IL6 polymorphisms with lung function decline and COPD.

{{PMID|19750100|OA=1
}} Modification of the interleukin-6 response to air pollution by interleukin-6 and fibrinogen polymorphisms.

{{PMID|20011102|OA=1
}} Fine-scale variation and genetic determinants of alternative splicing across individuals.

{{PMID Auto
|PMID=23251429
|Title=Inflammation and immune-related candidate gene associations with acute lung injury susceptibility and severity: a validation study.
|OA=1
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}