{{Rsnum
|rsid=2070106
|Gene=CNP
|Chromosome=17
|position=41973846
|Orientation=plus
|ReferenceAllele=G
|GMAF=0.2626
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=CNP
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 15.9 | 47.8 | 36.3
| HCB | 7.3 | 46.7 | 46.0
| JPT | 13.3 | 46.0 | 40.7
| YRI | 0.7 | 7.5 | 91.8
| ASW | 1.8 | 42.1 | 56.1
| CHB | 7.3 | 46.7 | 46.0
| CHD | 17.4 | 51.4 | 31.2
| GIH | 14.9 | 48.5 | 36.6
| LWK | 0.0 | 14.5 | 85.5
| MEX | 6.9 | 29.3 | 63.8
| MKK | 1.9 | 25.6 | 72.4
| TSI | 2.9 | 37.3 | 59.8
| HapMapRevision=28
}}

Based on a study of 790 individuals from 245 nuclear families (220 families were European Caucasian; 300 of the probands had a diagosis of [[schizophrenia]]), the [[rs2070106]](G) allele was overtransmitted to affected offspring.{{PMID|18496213}} 

This actually conflicts with a previous report {{PMID|16389193}} in which the [[rs2070106]](A) allele was identified (also in Caucasians) in a combined gene association/expression study as associated with [[schizophrenia]].

This is either a case of the "flip-flop" phenomenon {{PMID|17273975|OA=1
}} in which multilocus effects and variation in interlocus correlations reverse a previously reported association, or perhaps more likely, a false positive.

{{PMID Auto
|PMID=17306456
|Title=Case-control association study of the 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP) gene and schizophrenia in the Han Chinese population.
}}

{{PMID Auto
|PMID=17964117
|Title=Expression of oligodendrocyte-associated genes in dorsolateral prefrontal cortex of patients with schizophrenia.
|OA=1
}}

{{PMID Auto
|PMID=18289148
|Title=Effect of a functional single nucleotide polymorphism in the 2',3'-cyclic nucleotide 3'-phosphodiesterase gene on the expression of oligodendrocyte-related genes in schizophrenia.
}}

{{PMID Auto
|PMID=19348671
|Title=No relationship between 2',3'-cyclic nucleotide 3'-phosphodiesterase and schizophrenia in the Chinese Han population: an expression study and meta-analysis.
|OA=1
}}

{{PMID Auto
|PMID=22473874
|Title=A myelin gene causative of a catatonia-depression syndrome upon aging.
|OA=1
}}

{{PMID Auto
|PMID=23032943
|Title=The association of white matter volume in psychotic disorders with genotypic variation in NRG1, MOG and CNP: a voxel-based analysis in affected individuals and their unaffected relatives
|OA=1
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}