{{Rsnum
|rsid=2072590
|Gene=LOC401022
|Chromosome=2
|position=176177905
|Orientation=minus
|GMAF=0.2378
|Gene_s=HOXD-AS1
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(G;G)
|geno2=(G;T)
|geno3=(T;T)
}}[[rs2072590]] is a SNP on chromosome 2q31, in a noncoding region ~5 kb distal to the [[HOXD3]] gene and ~10 kb proximal to [[HOXD1]]. 

A genome-wide association study ultimately including over 10,000 [[ovarian cancer]] patients found statistically strong (p = 3.8 × 10e?14) evidence for slightly elevated risk associated with the [[rs2072590]](T) allele, with an odds ratio of 	1.20 (CI: 1.14–1.25) as calculated for the serous subtype (of ovarian cancer), though it was significant for the other subtypes as well.{{PMID|20852632|OA=1
}}

{{ population diversity
| geno1=(G;G)
| geno2=(G;T)
| geno3=(T;T)
| CEU | 40.2 | 47.3 | 12.5
| HCB | 47.8 | 44.9 | 7.4
| JPT | 61.9 | 33.6 | 4.4
| YRI | 92.5 | 7.5 | 0.0
| ASW | 84.2 | 14.0 | 1.8
| CHB | 47.8 | 44.9 | 7.4
| CHD | 56.0 | 35.8 | 8.3
| GIH | 71.3 | 27.7 | 1.0
| LWK | 82.7 | 16.4 | 0.9
| MEX | 65.5 | 25.9 | 8.6
| MKK | 87.8 | 12.2 | 0.0
| TSI | 43.6 | 45.5 | 10.9
| HapMapRevision=28
}}{{PMID Auto GWAS
|PMID=20852632
|Trait=None
|Title=A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24
|RiskAllele=T
|Pval=5E-14
|OR=1.16
|ORtxt=[1.12-1.21]
|OA=1
}}

{{PMID Auto
|PMID=22235027
|Title=Evaluation of microRNA expression profiles and their associations with risk alleles in lymphoblastoid cell lines of familial ovarian cancer.
|OA=1
}}

{{PMID Auto GWAS
  |PMID=23535730
  |Trait=Ovarian cancer
  |Title=GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer.
  |RiskAllele=
  |Pval=3E-10
  |OR=1.13
  |ORtxt=[1.09-1.18]
  |OA=1
}}

{{PMID Auto
|PMID=23133607
|Title=Associations between gene expression variations and ovarian cancer risk alleles identified from genome wide association studies.
|OA=1
}}

{{PMID Auto
|PMID=25173882
|Title=Replication Study for the Association of Seven Genome- Gwas-Identified Loci With Susceptibility to Ovarian Cancer in the Polish Population
}}
{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Illumina Human 1M}}