{{Rsnum
|rsid=2073440
|Gene=HDC
|Chromosome=15
|position=50242317
|Orientation=minus
|ReferenceAllele=A
|MissenseAllele=C
|GMAF=0.06657
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;C)
|geno3=(C;C)
|Gene_s=HDC
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;C)
| geno3=(C;C)
| CEU | 92.9 | 6.2 | 0.9
| HCB | 84.7 | 15.3 | 0.0
| JPT | 92.9 | 7.1 | 0.0
| YRI | 67.3 | 31.3 | 1.4
| ASW | 80.0 | 20.0 | 0.0
| CHB | 84.7 | 15.3 | 0.0
| CHD | 80.7 | 15.6 | 3.7
| GIH | 0.0 | 0.0 | 0.0
| LWK | 65.5 | 28.2 | 6.4
| MEX | 98.3 | 1.7 | 0.0
| MKK | 57.7 | 39.1 | 3.2
| TSI | 98.0 | 2.0 | 0.0
| HapMapRevision=28
}}{{PMID Auto
|PMID=19450133
|Title=Histamine pharmacogenomics
}}

{{PMID Auto
|PMID=18853455
|Title=Whole genome survey of coding SNPs reveals a reproducible pathway determinant of Parkinson disease.
|OA=1
}}

{{PMID Auto
|PMID=20608921
|Title=Variability of the L-Histidine decarboxylase gene in allergic rhinitis.
}}

{{GET Evidence
|gene=HDC
|aa_change=Glu644Asp
|aa_change_short=E644D
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs2073440
|overall_frequency_n=673
|overall_frequency_d=10758
|overall_frequency=0.0625581
|n_genomes=7
|n_genomes_annotated=0
|n_haplomes=8
|n_articles=0
|n_articles_annotated=0
|pph2_score=0.877
|nblosum100=-2
|autoscore=1
|webscore=N
}}

{{PMID Auto
|PMID=23152756
|Title=The Diamine Oxidase Gene Is Associated with Hypersensitivity Response to Non-Steroidal Anti-Inflammatory Drugs
|OA=1
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}