{{Rsnum
|rsid=2074190
|Gene=TBX21
|Chromosome=17
|position=47733844
|Orientation=plus
|ReferenceAllele=A
|GMAF=0.2401
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=TBX21
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 4.4 | 38.9 | 56.6
| HCB | 2.2 | 19.3 | 78.5
| JPT | 0.9 | 12.4 | 86.7
| YRI | 9.7 | 43.4 | 46.9
| ASW | 10.7 | 33.9 | 55.4
| CHB | 2.2 | 19.3 | 78.5
| CHD | 0.9 | 18.3 | 80.7
| GIH | 11.9 | 44.6 | 43.6
| LWK | 7.3 | 43.1 | 49.5
| MEX | 8.8 | 56.1 | 35.1
| MKK | 18.1 | 49.0 | 32.9
| TSI | 14.7 | 33.3 | 52.0
| HapMapRevision=28
}}[[rs2074190(G;G)]] and [[rs2074190(A;G)]] genotypes for the [[TBX21]] gene are calculated to be at 2.19 fold higher risk (CI: 1.27-3.77) for aspirin-induced [[asthma]] (AIA) compared to [[rs2074190(A;A)]] homozygotes, based on a study of 72 patients vs 640 controls in a study of a Japanese population. {{PMID|15806396}}

Note that in this population, but perhaps not others, linkage disequilibrium exists between this SNP located in the first exon, [[rs2074190]], and a SNP located upstream of the gene, [[rs4794067]], with a predictive accuracy of 92%.
{{ neighbor
| rsid = 2240017
| distance = 291
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}