{{Rsnum
|rsid=2074238
|Gene=KCNQ1
|Chromosome=11
|position=2463573
|Orientation=plus
|GMAF=0.04178
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=KCNQ1
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 88.7 | 9.7 | 1.6
| HCB | 97.8 | 2.2 | 0.0
| JPT | 90.9 | 9.1 | 0.0
| YRI | 100.0 | 0.0 | 0.0
| ASW | 0.0 | 0.0 | 0.0
| CHB | 97.8 | 2.2 | 0.0
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 0.0 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}[http://blog.23andme.com/2009/03/23/snpwatch-researchers-identify-genetic-variants-linked-to-heart-rhythm-and-possibly-sudden-cardiac-death/ 23andMe blog] Influences [[QT interval]]

{{PMID Auto GWAS
|PMID=19305408
|Trait=QT interval
|Title=Common variants at ten loci influence QT interval duation in the QTGEN Study
|RiskAllele=T
|Pval=3E-17
|OR=7.88
|ORtxt=[6.16-9.59] msec decrease
|OA=1
}}

{{PharmGKB
|RSID=rs2074238
|Name_s=
|Gene_s=KCNQ1
|Feature=
|Evidence=PubMed ID:19305408; Web Resource:http://www.genome.gov/gwastudies/
|Annotation=GWAS results: Common variants at ten loci influence QT interval duation in the QTGEN Study. (Initial Sample Size: 13,685 individuals; Replication Sample Size: 15,854 individuals); (Region: 11p15.5; Reported Gene(s): KCNQ1; Risk Allele: rs2074238-T); (p-value= 0.00000000000000003).This variant is associated with QT interval.
|Drugs=
|Drug Classes=
|Diseases=
|Curation Level=Non-Curated
|PharmGKB Accession ID=PA164739891
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs2074238
|overall_frequency_n=118
|overall_frequency_d=124
|overall_frequency=0.951613
|n_genomes=53
|n_genomes_annotated=0
|n_haplomes=101
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|in_pharmgkb=Y
|autoscore=2
|webscore=N
}}

{{PMID Auto
|PMID=23856471
|Title=Identification of a KCNQ1 polymorphism acting as a protective modifier against arrhythmic risk in long-QT syndrome.
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}