{{Rsnum
|rsid=2074518
|Gene=LIG3
|Chromosome=17
|position=34997363
|Orientation=minus
|GMAF=0.3255
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=LIG3
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 23.0 | 55.8 | 21.2
| HCB | 10.2 | 38.0 | 51.8
| JPT | 1.8 | 34.5 | 63.7
| YRI | 0.7 | 17.1 | 82.2
| ASW | 1.8 | 35.1 | 63.2
| CHB | 10.2 | 38.0 | 51.8
| CHD | 6.4 | 43.1 | 50.5
| GIH | 16.8 | 42.6 | 40.6
| LWK | 0.0 | 19.3 | 80.7
| MEX | 13.8 | 53.4 | 32.8
| MKK | 0.6 | 21.8 | 77.6
| TSI | 21.6 | 44.1 | 34.3
| HapMapRevision=28
}}
[http://blog.23andme.com/2009/03/23/snpwatch-researchers-identify-genetic-variants-linked-to-heart-rhythm-and-possibly-sudden-cardiac-death/ 23andMe blog] Influences [[QT interval]]

{{PMID Auto GWAS
|PMID=19305408
|Trait=QT interval
|Title=Common variants at ten loci influence QT interval duation in the QTGEN Study
|RiskAllele=T
|Pval=6E-12
|OA=1
}}

{{PharmGKB
|RSID=rs2074518
|Name_s=
|Gene_s=LIG3
|Feature=
|Evidence=PubMed ID:19305408; Web Resource:http://www.genome.gov/gwastudies/
|Annotation=GWAS results: Common variants at ten loci influence QT interval duation in the QTGEN Study. (Initial Sample Size: 13,685 individuals; Replication Sample Size: 15,854 individuals); (Region: 17q12; Reported Gene(s): LIG3,RFFL; Risk Allele: rs2074518-T); (p-value= 0.000000000006).This variant is associated with QT interval.
|Drugs=
|Drug Classes=
|Diseases=
|Curation Level=Non-Curated
|PharmGKB Accession ID=PA164739889
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs2074518
|overall_frequency_n=45
|overall_frequency_d=128
|overall_frequency=0.351562
|n_genomes=28
|n_genomes_annotated=0
|n_haplomes=36
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|in_pharmgkb=Y
|autoscore=2
|webscore=N
}}

{{on chip | Illumina Human 1M}}