{{Rsnum
|rsid=2075685
|Gene=TMEM167A
|Chromosome=5
|position=83076846
|Orientation=plus
|GMAF=0.3852
|Gene_s=TMEM167A,XRCC4
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(G;G)
|geno2=(G;T)
|geno3=(T;T)
}}{{ population diversity
| geno1=(G;G)
| geno2=(G;T)
| geno3=(T;T)
| CEU | 21.2 | 51.3 | 27.4
| HCB | 64.2 | 32.1 | 3.6
| JPT | 55.8 | 36.3 | 8.0
| YRI | 19.0 | 53.7 | 27.2
| ASW | 15.8 | 56.1 | 28.1
| CHB | 64.2 | 32.1 | 3.6
| CHD | 60.6 | 34.9 | 4.6
| GIH | 14.9 | 41.6 | 43.6
| LWK | 28.2 | 43.6 | 28.2
| MEX | 50.0 | 39.7 | 10.3
| MKK | 26.3 | 48.7 | 25.0
| TSI | 34.3 | 39.2 | 26.5
| HapMapRevision=28
}}18067C>T possibly related to non-Hodgkin lymphoma

{{PMID|18410587}}  [[rs2040639]]-AG, contribute to oral cancer risk. 

pseudo-haplotype with AG-CC genotypes in 
*2.45x risk [[rs2040639]]-[[rs861539]]
*5.03x risk [[rs2040639]]-[[rs861539]]-[[rs2075685]]
*10.10x risk [[rs2040639]]-[[rs861539]]-[[rs2075685]]-[[rs1799782]]

{{PMID Auto
|PMID=19443403
|Title=Significant Association of an XRCC4 Single Nucleotide Polymorphism with Bladder Cancer Susceptibility in Taiwan
}}; '''note:''' no association found for this SNP

{{PMID Auto
|PMID=19729825
|Title=Lung cancer susceptibility and genetic polymorphism of DNA repair gene XRCC4 in Taiwan
}}

{{PMID Auto
|PMID=20332465
|Title=Significant association of XRCC4 single nucleotide polymorphisms with childhood leukemia in Taiwan
}}
{{PMID Auto
|PMID=20683005
|Title=Colorectal Cancer and Genetic Polymorphism of DNA Double-strand Break Repair Gene XRCC4 in Taiwan
}}

{{PMID Auto
|PMID=21296624
|Title=An analysis of single nucleotide polymorphisms of 125 DNA repair genes in the Texas genome-wide association study of lung cancer with a replication for the XRCC4 SNPs
|OA=1
}}

{{PMID Auto
|PMID=22726897
|Title=Single nucleotide polymorphism barcoding to evaluate oral cancer risk using odds ratio-based genetic algorithms
}}

{{PMID Auto
|PMID=19276285
|Title=Associations between single nucleotide polymorphisms in double-stranded DNA repair pathway genes and familial breast cancer.
|OA=1
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}