{{Rsnum
|rsid=2082412
|Chromosome=5
|position=159290781
|Orientation=plus
|GMAF=0.3563
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 0.9 | 37.2 | 61.9
| HCB | 14.6 | 54.7 | 30.7
| JPT | 30.1 | 47.8 | 22.1
| YRI | 15.6 | 48.3 | 36.1
| ASW | 12.3 | 50.9 | 36.8
| CHB | 14.6 | 54.7 | 30.7
| CHD | 19.3 | 48.6 | 32.1
| GIH | 12.9 | 39.6 | 47.5
| LWK | 21.8 | 52.7 | 25.5
| MEX | 19.0 | 37.9 | 43.1
| MKK | 8.3 | 55.1 | 36.5
| TSI | 7.8 | 37.3 | 54.9
| HapMapRevision=28
}}
{{PMID Auto GWAS
|PMID=19169254
|Trait=Psoriasis
|Title=Genome-wide scan reveals association of psoriasis with IL-23 and NF-kappaB pathways
|RiskAllele=G
|Pval=2E-28
|OR=1.44
|ORtxt=None
|OA=1
}}

{{omim
|desc=PSORIASIS SUSCEPTIBILITY 11; PSORS11
|id=612599
|rsnum=2082412
}}

{{PharmGKB
|RSID=rs2082412
|Name_s=
|Gene_s=-
|Feature=
|Evidence=PubMed ID:19169254; Web Resource:http://www.genome.gov/gwastudies/
|Annotation=GWAS results: Genome-wide scan reveals association of psoriasis with IL-23 and NF-kappaB pathways. (Initial Sample Size: 1,359 cases, 1,400 controls; Replication Sample Size: 5,048 cases, 5,041 controls); (Region: 5q33.3; Reported Gene(s): IL12B; Risk Allele: rs2082412-G); (p-value= 2E-28).This variant is associated with Psoriasis.
|Drugs=
|Drug Classes=
|Diseases=Psoriasis
|Curation Level=Non-Curated
|PharmGKB Accession ID=PA164740042
}}

{{PMID Auto
|PMID=19262574
|Title=Genome-wide association scan yields new insights into the immunopathogenesis of psoriasis.
|OA=1
}}

{{PMID Auto
|PMID=20606885
|Title=Genetics of psoriasis and psoriatic arthritis.
|OA=1
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs2082412
|overall_frequency_n=40
|overall_frequency_d=128
|overall_frequency=0.3125
|n_genomes=31
|n_genomes_annotated=0
|n_haplomes=36
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|in_pharmgkb=Y
|autoscore=2
|webscore=N
}}

{{PMID Auto
|PMID=23252691
|Title=Investigation of 20 non-HLA (human leucocyte antigen) psoriasis susceptibility loci in Chinese patients with psoriatic arthritis and psoriasis vulgaris.
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}