{{Rsnum
|rsid=2116078
|Chromosome=8
|position=72451754
|Orientation=plus
|GMAF=0.3903
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(G;G)
|geno2=(G;T)
|geno3=(T;T)
}}{{ population diversity
| geno1=(G;G)
| geno2=(G;T)
| geno3=(T;T)
| CEU | 30.1 | 47.8 | 22.1
| HCB | 7.3 | 46.0 | 46.7
| JPT | 9.7 | 45.1 | 45.1
| YRI | 0.7 | 26.5 | 72.8
| ASW | 3.5 | 43.9 | 52.6
| CHB | 7.3 | 46.0 | 46.7
| CHD | 8.3 | 30.3 | 61.5
| GIH | 15.8 | 36.6 | 47.5
| LWK | 4.5 | 36.4 | 59.1
| MEX | 24.1 | 48.3 | 27.6
| MKK | 7.7 | 39.7 | 52.6
| TSI | 32.4 | 45.1 | 22.5
| HapMapRevision=28
}}
{{PMID Auto GWAS
|PMID=19010793
|Trait=Multiple sclerosis (age of onset)
|Title=Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis
|RiskAllele=
|Pval=0.000003
|OR=NR
|ORtxt=NR
}}

{{PharmGKB
|RSID=rs2116078
|Name_s=
|Gene_s=-
|Feature=
|Evidence=PubMed ID:19010793; Web Resource:http://www.genome.gov/gwastudies/
|Annotation=GWAS results: Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis. (Initial Sample Size: 978 cases, 883 controls; Replication Sample Size: NR); (Region: 8q13.3; Reported Gene(s): KCNB2; Risk Allele: rs2116078-?); (p-value= 0.000003).This variant is associated with Multiple sclerosis (age of onset).
|Drugs=
|Drug Classes=
|Diseases=Multiple Sclerosis
|Curation Level=Non-Curated
|PharmGKB Accession ID=PA164740719
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs2116078
|overall_frequency_n=51
|overall_frequency_d=122
|overall_frequency=0.418033
|n_genomes=34
|n_genomes_annotated=0
|n_haplomes=46
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|in_pharmgkb=Y
|autoscore=2
|webscore=N
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Illumina Human 1M}}