{{Rsnum
|rsid=2145418
|Chromosome=1
|position=118422631
|Orientation=minus
|GMAF=0.2557
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(G;G)
|geno2=(G;T)
|geno3=(T;T)
}}{{ population diversity
| geno1=(G;G)
| geno2=(G;T)
| geno3=(T;T)
| CEU | 4.4 | 31.0 | 64.6
| HCB | 5.8 | 39.4 | 54.7
| JPT | 2.7 | 38.1 | 59.3
| YRI | 12.9 | 38.8 | 48.3
| ASW | 7.0 | 45.6 | 47.4
| CHB | 5.8 | 39.4 | 54.7
| CHD | 5.6 | 50.0 | 44.4
| GIH | 1.0 | 32.7 | 66.3
| LWK | 3.6 | 42.7 | 53.6
| MEX | 21.1 | 36.8 | 42.1
| MKK | 8.3 | 38.5 | 53.2
| TSI | 4.9 | 28.4 | 66.7
| HapMapRevision=28
}}
[[rs2145418]] is a SNP in the chromosome 1p12-13 region.

In a case-control association study in a Spanish population, [[rs2145418]] was associated with increased risk for [[thyroid cancer]]. [[rs2145418]](G;T) heterozygotes had an odds ratio of 5.0 (CI: 2.85 - 8.83), while (G;G) homozygotes had an increased odds ratio of 9.2 (CI: 4.50 - 21.6), with reported significance of p < 0.0001.{{PMID|18559567}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}