{{Rsnum
|rsid=2149356
|Gene=TLR4
|Chromosome=9
|position=117711921
|Orientation=minus
|GMAF=0.45
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;C)
|geno3=(C;C)
|Gene_s=TLR4
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;C)
| geno3=(C;C)
| CEU | 12.3 | 30.8 | 56.9
| HCB | 6.8 | 59.1 | 34.1
| JPT | 13.3 | 37.8 | 48.9
| YRI | 68.3 | 27.0 | 4.8
| ASW | 0.0 | 0.0 | 0.0
| CHB | 6.8 | 59.1 | 34.1
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 0.0 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}{{PMID Auto
|PMID=21081146
|Title=Impact of Toll-like receptor 4 polymorphisms on risk of cancer
}}

{{PMID Auto
|PMID=21921986
|Title=Toll-like receptor 4 gene polymorphisms do not associate with normal tension glaucoma in a Korean population
|OA=1
}}

{{PMID Auto
|PMID=22251849
|Title=The association of Toll-like receptor 4 gene polymorphisms with the development of emphysema in Japanese subjects: a case control study
|OA=1
}}

{{PMID Auto
|PMID=22272615
|Title=Common variants in toll-like receptor 4 confer susceptibility to Alzheimer's disease in a Han Chinese population
}}

{{PMID Auto
|PMID=22286521
|Title=Polymorphism of the TLR4 Gene Reduces the Risk of Hepatitis C Virus-Induced Hepatocellular Carcinoma
}}

{{PMID Auto
|PMID=18298826
|Title=Association between variations in the TLR4 gene and incident type 2 diabetes is modified by the ratio of total cholesterol to HDL-cholesterol.
|OA=1
}}

{{PMID Auto
|PMID=18586872
|Title=Association of Toll-like receptor 4 gene polymorphisms with normal tension glaucoma.
}}

{{PMID Auto
|PMID=19131814
|Title=Variation in the TLR4 gene influences the risk of organ failure and shock posttrauma: a cohort study.
|OA=1
}}

{{PMID Auto
|PMID=19500628
|Title=Association analysis of Toll-like receptor 4 polymorphisms with autoimmune pancreatitis.
}}

{{PMID Auto
|PMID=19505919
|Title=Toll-like receptor signaling pathway variants and prostate cancer mortality.
|OA=1
}}

{{PMID Auto
|PMID=19543401
|Title=Toll-like receptor polymorphisms and susceptibility to urinary tract infections in adult women.
|OA=1
}}

{{PMID Auto
|PMID=20011079
|Title=Lack of association between toll-like receptor 4 gene polymorphisms and sarcoidosis-related uveitis in Japan.
|OA=1
}}

{{PMID Auto
|PMID=20200442
|Title=Sequence variants in the TLR4 and TLR6-1-10 genes and prostate cancer risk. Results based on pooled analysis from three independent studies.
|OA=1
}}

{{PMID Auto
|PMID=20463618
|Title=Role of polymorphic variants as genetic modulators of infection in neonatal sepsis.
|OA=1
}}

{{PMID Auto
|PMID=23084080
|Title=The TLR4 gene polymorphisms and susceptibility to cancer: A systematic review and meta-analysis
}}

{{PMID Auto
|PMID=23738004
|Title=Association of TLR4 Gene rs2149356 Polymorphism with Primary Gouty Arthritis in a Case-Control Study
|OA=1
}}

{{PMID Auto
|PMID=22831837
|Title=Association of Toll-like receptor 4 gene polymorphisms in Japanese subjects with primary open-angle, normal-tension, and exfoliation glaucoma.
}}

{{PMID Auto
|PMID=24929142
|Title=Genetic polymorphisms in the Toll-like receptor signalling pathway in Helicobacter pylori infection and related gastric cancer
}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}