{{Rsnum
|rsid=2160525
|Gene=LRP6
|Chromosome=12
|position=12117356
|Orientation=plus
|GMAF=0.1373
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=LRP6
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 3.5 | 31.0 | 65.5
| HCB | 1.5 | 19.0 | 79.6
| JPT | 0.0 | 12.5 | 87.5
| YRI | 5.4 | 27.2 | 67.3
| ASW | 1.8 | 31.6 | 66.7
| CHB | 1.5 | 19.0 | 79.6
| CHD | 0.9 | 8.3 | 90.8
| GIH | 1.0 | 15.8 | 83.2
| LWK | 3.6 | 27.3 | 69.1
| MEX | 1.7 | 13.8 | 84.5
| MKK | 7.7 | 35.9 | 56.4
| TSI | 2.9 | 30.4 | 66.7
| HapMapRevision=28
}}{{Report GE
|PubMed=17517621
|Source=pubmed
|AffyProbeset=SNP_A-1861148
|AffyOrientation=same
|AlleleA=A
|AlleleB=G
|onGW5=1
|rsid=2160525
|ancestral=G
|RiskPopulation=Caucasian
|RiskAllele=G
|CaseFreq=0.85
|ControlFreq=0.81
|OddsRatioHet=
|OddsRatioHom=
|OddsRatioAll=1.30
|Disease=Alzheimer's disease, late-onset
|DiseaseSymbol=LOAD
|OA=1
}}

rs2160525 is in linkage disequilibrium with a polymorphism that increases susceptibility to late-onset [[Alzheimer's disease]] (LOAD) 1.30 times for carriers of the G allele. {{PMID|17517621|OA=1
}}

{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | Affy500k}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}