{{Rsnum
|rsid=2161983
|Gene=ACVR2A
|Chromosome=2
|position=147891817
|Orientation=minus
|GMAF=0.3953
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=ACVR2A
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 40.6 | 53.1 | 6.2
| HCB | 16.3 | 67.4 | 16.3
| JPT | 24.4 | 51.2 | 24.4
| YRI | 57.9 | 33.3 | 8.8
| ASW | 0.0 | 0.0 | 0.0
| CHB | 16.3 | 67.4 | 16.3
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 0.0 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}This SNP is located on chromosome 2q22-23, in the activin receptor type 2 gene ([[ACVR2A]]) gene.

A study of 1139 Norwegian women with one or more pre-eclamptic pregnancies and 2269 controls (women with normal pregnancies) identified four SNPs in this region ([[rs1424941]], [[rs1014064]], [[rs2161983]] and [[rs3768687]]) as associated with higher risk for [[pre-eclampsia]].

{{PMID|18781190|OA=1
}} Association between the candidate susceptibility gene ACVR2A on chromosome 2q22 and pre-eclampsia in a large Norwegian population-based study (the HUNT study).

{{PMID|19126782|OA=1
}} Genetic association of the activin A receptor gene (ACVR2A) and pre-eclampsia.

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}